颅内静脉血栓形成患者脑脊液细胞学特点  

The cerebrospinal fluid cytology characteristic of patient suffering cerebral venous ssinus thrombosis

作　　者：董瑞芳[1] 张兵[2] 台立稳[1] 冯晓[1] 李培[1] 何俊瑛[1] 

机构地区：[1]河北医科大学附属第二医院神经内科,石家庄050000 [2]南京医科大学附属鼓楼医院神经内科

出　　处：《脑与神经疾病杂志》2009年第2期97-100,共4页Journal of Brain and Nervous Diseases

基　　金：河北省科技厅指导课题资助项目(10527612197)

摘　　要：目的探讨脑脊液细胞学检查对颅内静脉血栓形成的临床诊断价值。方法对4例不同原因引起的颅内静脉血栓形成患者应用细胞玻片离心沉淀法进行脑脊液细胞学检查,并结合相关文献进行分析。结果本组4例患者以不同方式起病,病因各有不同,临床表现各异,但都伴有颅高压症状,腰穿压力增高,脑脊液细胞学可见数量不等的红细胞,2例患者脑脊液中还可见红细胞吞噬细胞和含铁血黄素吞噬细胞。结论观察颅内静脉血栓形成患者脑脊液细胞学变化有利于该疾病的临床诊断,尤其对于症状不典型且MRV上未显示明确颅内静脉异常及脑深部静脉血栓病人更具有临床价值。Objective To discuss the cerebrospinal fluid cytology＇s sense in clinical diagnosis for cerebral venoug sinus thrombosis （ CVST）. Methods Report the cerebrospinal fluid cytology characteristic of four patients with Intracranial venous thrombosis originated by different reasons, and review pertinent literature. Results Four patient have different onset way,different cause of disease and different clinical manifestation,but all of them accom- pany intracranial hypertension, increased pressure and unequal amount of red blood cell in cerebrospinal fluid cytolo- gy examination. Some of them show erythrophage hemosiderin phagocytic cell in the CSF. Conclusion Observing the variation of the patient＇s CSF is good for clinical diagnosis of Intraeranial venous thrombosis, especially for the people who have no-typical symptom and stricture of vein in MRVor with deep vein thrombosis in brain, but DSA is still the most trustworthy method for Intracranial venous thrombosis.

关 键 词：颅内静脉血栓形成 脑脊液细胞学 诊断 

分 类 号：R743.32[医药卫生—神经病学与精神病学]