脑出血患者早期血肿扩大相关危险因素的临床分析  

The clinical analysis of risk factors on hematoma enlargement inpatients with intracerebral hemorrhage

作　　者：刘青蕊[1] 王新存[2] 崔鹏[1] 米小昆[1] 

机构地区：[1]河北医科大学第四医院神经内科,石家庄050011 [2]河南省濮阳市人民医院内科

出　　处：《脑与神经疾病杂志》2009年第2期133-136,共4页Journal of Brain and Nervous Diseases

摘　　要：目的探讨脑出血后早期血肿增大的相关危险因素。方法299例脑出血患者,根据病情演变及脑CT变化,分为血肿增大组和血肿稳定组,对两组患者病史、临床特点、生化指标及头颅CT特征进行对比分析。结果299例患者中,69例出现血肿增大,发生率为23%,其中23例发生在24h内;基底节区不规则血肿、血压持续升高、肝功能受损、大量饮酒及长期口服抗血小板聚集药物的患者,易发生血肿扩大,两组比较有显著性差异(P(0.05)。结论脑出血后血肿增大多发生在24h内,长期口服抗血小板聚集药物、发病后血压持续增高、肝功能受损可能为血肿增大的主要危险因素。Objective To investigate the risk factors of early hematoma enlargement （HE） after intracere- bral hemorrhage and treatment measures. Methods Two hundred and nity-nine patients with intracerebral hemor- rhage （ICH） , according to clinical features and brain CT change, were divided into two groups （ HE group and sta- ble group）. The history of patients, clinical characteristics, biochemical parameters of blood and CT features were analyzed and compared in two groups. Results Sixty-nine patients in 299 had sustained hematoma increased and the incidence was 23 percent , of which 23 cases occurred within 24h . The patients with basal ganglia irregular hema- toma ,permanent high blood pressure, impaired liver function, excessive alcohol intake and long-term oral antithrom- botic drugs in HE group were higher than that in hematoma stable group. There was more significant difference in two groups（P 〈 0.05）, Conclusion Hematoma enlargement in ICH more occurs in 24h. Long-term oral antithrombotic drug, increased blood pressure after onset, liver function impairment may be the main risk factors of hematoma in- creased.

关 键 词：脑出血 血肿增大 危险因素 

分 类 号：R743.34[医药卫生—神经病学与精神病学]