血管内支架成形术在76例椎动脉开口狭窄患者中的临床观察与随访  

Follow-up study after transluminal stent-assisted angioplasty for 76 patients with vertebral artery stenosis

作　　者：张俊玲[1] 白锡波[1] 张乐国[1] 李阔[1] 

机构地区：[1]沧州市中心医院神经内二科,河北061001

出　　处：《脑与神经疾病杂志》2009年第4期249-252,共4页Journal of Brain and Nervous Diseases

基　　金：河北省卫生厅2008年医学科学研究重点课题计划(08205)

摘　　要：目的通过观察血管内支架成形术在治疗椎动脉开口狭窄患者中的短期疗效,探讨其安全性与有效性。方法对76例经DSA或CTA证实椎动脉开口处狭窄并符合支架植入指征的患者实施血管内支架植入,观察血管狭窄程度在术前、术后和术后6个月的变化,以及相关并发症。术后随访6个月,行Malek评分。结果76例患者椎动脉开口狭窄率从术前平均82.3±14.2%下降至术后的11.5±9.8%,除3例出现穿刺点皮下血肿,未发生其它围手术期并发症。在6个月的临床随访中,69例患者症状明显改善,2例患者发生再狭窄,Malek评分显著改善。结论血管内支架成形术治疗椎动脉开口狭窄是一种安全有效的方法,但远期疗效仍需要前瞻性大规模的临床研究。Objective To discuss the safety and effectiveness of transluminal stent-assisted angioplasty treatment on symptomatic vertebral artery stenosis through short-term Follow-up. Methods 76 patients with vertebral artery stenosis,identified by DSA or CTA, who were treated by transluminal stent-assisted angioplasty were choosed. We observed the stenosis changement at preoperative, postoperative and 6 months after treated. Complications were also observed in 6 months Follow-up after treated, and Malek evaluation was adopted at 6 months after treated. Results The stenosis rate reduced to about 11% （ 11.5 ± 9.8% ） after PTAS （ 82.3 ±14.2% before PTAS）. No serious procedure-related complications happened except 3 patients with Subcutaneous hematoma of Puncture points. In 6 months Follow-up, 69 patients improved obviously, but 2 patients occoured restenosis. Malek evaluation also proved significant improvement. Conclusion Endovascular stenting for vertebral artery stenosis is effective and safe within short-periods. But long-term results still have no conclustion and large prospective observational study is needed.

关 键 词：椎动脉狭窄 支架 血管成形术 临床观察 随访 

分 类 号：R743[医药卫生—神经病学与精神病学]