丝裂霉素C及可调节缝线在小梁切除术中的临床应用  

Clinical Research on the Application of Mitomycin C and Adjustable Sutures in Trabeculectomy

作　　者：胡富生[1] 刘菲[1] 钱爱军[1] 

机构地区：[1]解放军第169医院眼科,湖南衡阳421002

出　　处：《临床军医杂志》2009年第4期662-664,共3页Clinical Journal of Medical Officers

摘　　要：目的评价在青光眼小梁切除术中联合应用丝裂霉素C和可调节缝线的效果。方法将115例122眼各种类型青光眼患者随机分组。实验组78眼行小梁切除术,术中应用丝裂霉素C联合巩膜瓣可调节缝线,对其术后疗效进行观察及随访;对照组44眼行常规小梁切除术。结果实验组的眼压控制有效率、功能性滤过泡均高于对照组(P<0.01),浅前房的发生率比对照组少,差异有统计学意义(P<0.05),无明显并发症。结论小梁切除术中联合应用丝裂霉素C及可调节缝线可有效地控制眼压水平,减少巩膜瓣瘢痕及主动调节房水滤过量,促进功能性滤过泡形成,减少并发症,提高手术成功率。此术操作简便,易掌握,是治疗青光眼安全有效的方法之一。Objective To evaluate the effect of the combining application of mitomycin C and adjustable suture in trabeculectomy.Methods 115 glau-comatous patients（122 eyes） were randomly divided into two groups.78 eyes in experimental group were performed trabeculectomy,combined with application of mitomycin C and sclera flap sutured with an adjustalbe thread.44 eyes in control group were performed conventional tra-beculectomy.Results The controlled ratio of intraocular pressure and the functional filtering bleb in experimental group were significantly higher than those in control group（P〈0.01）;The occurrence rate of flat anterior chamber in experimental group was significantly lower than in the control group（P〈0.05）.There were no significant complications.Conclusion Trabecu-lectomy combined with mitomycin C and adjustable sutures can be effective in controlling intraocular pressure level,reducing scleral flap scarring,actively adjusting the volume of aqueous filtration,promoting the formation of the functional filtering bleb,reducing complications,improving the success rate of surgery.This performance is simple and ease to master,is an effective method of glaucoma treatment.

关 键 词：丝裂霉素C 可调节缝线 青光眼 小梁切除术 

分 类 号：R775[医药卫生—眼科]