颅底脊索瘤伽玛刀治疗后的MRI分析  

MRI Imaging of Basicranial Chordoma after Gamma Knife Radiosurgery

作　　者：周旭峰[1] 张丽雅[1] 卢超[1] 高志翔[1] 

机构地区：[1]洛阳市中心医院磁共振室,河南洛阳471009

出　　处：《实用放射学杂志》2009年第8期1100-1102,共3页Journal of Practical Radiology

摘　　要：目的探讨伽玛刀治疗颅底脊索瘤的临床疗效及MRI的影像学变化。方法回顾性分析13例行伽玛刀治疗后随访6年以上的颅底脊索瘤系列MRI资料，重点对肿瘤大小、MR信号特征以及临床症状的变化进行总结分析。评价MRI在颅底脊索瘤伽玛刀治疗后影像学变化中的作用。结果13例患者在治疗后1年内病灶逐渐缩小，其中2例在治疗后3个月左右病灶一过性增大；病灶信号逐渐变得均匀并失增强，T1wI病灶呈低信号，T2wI病灶呈明显高信号，其中4例与脑脊液信号相同。患者于治疗后1年内临床症状消失。结论MRI可以准确地照示颅底脊索瘤伽玛刀治疗后的病理演变及转归。Objective To evaluate the therapeutic effect of basicranial chordomas with gamma knife radiosurgery and the appearances on serial MR imaging. Methods The series MR imaging manifestations of basicranial chordoma in 13 cases were retrospectively analysed by followed up over 6 years after gamma knife radiosurgery. The changes of the size, signal characters of the tumors on plain and enhancement MR scans and clinic symptom were analysed. Results After radiotherapy, 13 lesions shrank gradually within one year and 2 lesions enlarged temporarily within 3 months or so, and signal intensity of the lesions became homogeneous and no enhancement. The lesions were hypointense on T1 WI and hyperintense on T2 WI, the signal intensity in 4 cases was similar to that of cerebrospinal fluid. The clinic symptoms of the patients were disappeared after radiotherapy within one year. Conclusion The changes of pathology of basicranial chordoma after Gamma knife radiosurgery are showed correctly by MRI.

关 键 词：脊索瘤 伽玛刀 疗效 磁共振成像 

分 类 号：R739.41[医药卫生—肿瘤] R815.2[医药卫生—临床医学]