生长抑素及其类似物对急性胰腺炎炎性反应调控的研究进展  

Progress of Somatostatin and Its Analogues on the Inflammatory Response in Acute Pancreatitis Control Research

作　　者：郝卫刚[1] 张海蓉[1] 段丽平[1] 

机构地区：[1]昆明医学院附属第一医院消化内科

出　　处：《医学综述》2009年第16期2415-2417,共3页Medical Recapitulate

摘　　要：在急性胰腺炎的病理过程中，各种炎性细胞在胰腺局部聚集并活化对胰腺炎的病情演变具有重要作用，适度的炎性反应有利于疾病的恢复，而过度激活的炎性反应是急性胰腺炎从胰腺局部病变迅速发展为全身炎性反应综合征和多器官功能障碍综合征的关键所在，生长抑素是临床上治疗急性胰腺炎的常用治疗药物之一，其对激活和失控的炎性反应过程具有广泛的调节作用。It plays an important role in the evolution of disease that various inflammatory cells gather and activate in the part of pancreas. Moderate inflammatory response is good to the recovery of disease, but overactivated inflammatory response is the criticality in the procession that acute pancreatitis development rapidly from local pathological changes to systemic inflammatory response syndrome and multiple organ dysfunction syndrome. Somatostatin is one of commonly used drugs that is used to therapy acute pancreatitis clinically, and has a widely adjust effect on its activation and out-of-control inflammatory reaction process.

关 键 词：生长抑素 全身性炎性反应综合征 代偿性抗炎性反应综合征 

分 类 号：R576[医药卫生—消化系统]