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机构地区:[1]暨南大学医学院附属清远市人民医院普外科,广东清远511500 [2]南华大学第一附属医院肿瘤外科,湖南衡阳421001
出 处:《岭南现代临床外科》2009年第4期265-267,共3页Lingnan Modern Clinics in Surgery
摘 要:目的探讨多原发结直肠癌的诊断与治疗方法。方法对多原发大肠癌24例进行回顾性分析。结果24例多原发大肠癌占同期收治结直肠癌的3.6%,共48处癌灶;其中同时癌为16例(2.4%),异时癌为8例(1.2%)。腺癌(34处)及腺瘤癌变(8处);癌肿位置以直肠、乙状结肠、升结肠居多。诊断确立即予规范手术及再次手术治疗,并积极术后化疗。5年生存率为56%。结论术前结肠镜检查,1术中仔细探查,术后定期随访复查是提高多原发结肠癌诊断率的关键;积极手术治疗5年生存率与单发癌提示无显著性差异。Objective To investigate the clinical features, diagnosis and treatment of the multiple primary colorectal carcinoma. Methods 24 patients with multiple primary colorectal cancers were analyzed retrospectively. Results 24 cases were accounting 3.6% of all patients with coloreetal cancer in the same period. There were 48 cancer foci in total. Among them 16 (2.4%) patients were synchronous carcinomas, and 8 (1.2%) patients were metachronous carcinomas. The majority were adenocarcinomas (34)eaneerfoci and carcinoma-changed adenomas (8). The 5 years survival rates were 56%. Conclusion Preoperative eolonoscopy,intraoperative exploration of whole colorectum and postoperative rechecking regularly were the important methods to improve the diagnosis rates of the multiple colorectal carcinomas. And active and correct operation are helpful to improve the prognosis of patients.
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