抑郁症患者药物治疗的成本-效果分析  

Cost-effectiveness analysis in the drug therapy of depressive patients

作　　者：陈敏[1] 张传芝[2] 张增[2] 叶萌[2] 王斌[2] 

机构地区：[1]济宁医学院精神卫生学院,山东济宁272013 [2]山东省安康医院,山东济宁272000

出　　处：《济宁医学院学报》2009年第4期256-258,共3页Journal of Jining Medical University

摘　　要：目的探讨抑郁症患者药物治疗方案的成本-效果。方法采用氟西汀、帕罗西汀、舍曲林、西酞普兰和氟伏沙明对150例抑郁症患者的治疗进行成本-效果分析。结果抑郁症患者治疗前的抑郁量表评分均值大于治疗后评分。药物经济学评价结果显示每个单位(C/E)的有效率-氟西汀组需要6.14元,帕罗西汀组需要6.98元,舍曲林组需要10.75元,西肽普兰组需要7.08元,氟伏沙明组需要7.34元。在所选择的五种药中氟西汀具有最好的成本效果,其次分别是帕罗西汀、西酞普兰和氟伏沙明,成本效果最低的是舍曲林。结论不同的抗抑郁药具有不同的成本-效果,在临床治疗中要予以充分重视。Objective：To study the cost-effectiveness in the drug therapy of depressive patients. Methods：l SO depressive patients were studied with fluoxetine, paroxetine, fluvoxamine, sertraline and citalopram to anylysis cost-effectiveness. Results：The depression scale score was greater than average score after treatment than that of before treatment. Pharmacoeconomic evaluation results showed that each unit （C / E） of efficient is as follows. Fluoxetine group need 6.14 yuan,paroxetine group need 6.98 yuan,sertraline group need 10.75 yuan, citalopram group need to 7.08 yuan,fluvoxamine group need to 7.34 yuan. In the choice of five kinds of drug fluoxetine with the best cost-effectiveness,followed by paroxetine, citalopram and fluvoxamine,and finally the sertraline. Conclusion：Different antidepressive drugs have different effect,so we must pay close attention in clinical work.

关 键 词：抑郁症 成本-效果 经济花费 

分 类 号：R749.7[医药卫生—神经病学与精神病学]