β-环糊精/萘酚对有机小分子识别作用研究  

Studies on Molecular Recognition for Small Organic Molecules by β-Cyclodextrin/naphthol

作　　者：陈金娥[1] 张海容[1] 

机构地区：[1]忻州师范学院生化分析技术研究所,山西忻州034000

出　　处：《山西大学学报（自然科学版）》2009年第3期443-446,共4页Journal of Shanxi University(Natural Science Edition)

基　　金：山西省自然科学基金(20051028);山西省归国留学基金(2008-90)

摘　　要：有机小分子甲醇、乙醇、丙醇、异丙醇、丁醇、丙酮、丁酮、乙腈、乙二醇在Britton-Robison三酸缓冲液中,不仅改变了β-环糊精(CD)空腔的微环境,而且使-βCD/萘酚超分子包合物的离解常数发生改变.文章用荧光法研究了主客体分子间的诱导契合和几何互补等方面β-环糊精/萘酚对小分子的结合能力和分子选择性.结果表明:β-环糊精/萘酚作为一种光谱探针可用于指示分子键合能力和分子识别能力.Effect of small organic molecules methanol, ethanol, n-propanol, 2-propanol, 1-butanol, acetone, butanone,acetonitrile and glycol on the cavity microenvironment of β-cyclodextrin and change of dissociation constants of β-cyclodextrin/naphthols supramolecular were determined in the Britton-Robison buffer solution by fluorescence,the bonded ability and molecular selectivity of β-cyclodextrin/naphthol supramolecular complex for small organic molecules have been discussed in inducing fit into the host-guest complex and the geometrical mutual benefit et al. The experiment indicated that the β-cyclodextrin/naphthol supramolecular complex as a spectrum probe can denote the bonded and discriminated abilities of molecules.

关 键 词：分子识别 萘酚 Β-环糊精 有机小分子 

分 类 号：O636.12[理学—高分子化学] O652.7[理学—化学]