多肿瘤标志物蛋白芯片诊断肺癌指标的筛查及应用  

Screening and Application of Associtive Marker Diagnosing Lung Cancer From Protein Chip Multi-Tumor Markers

作　　者：王坤[1] 

机构地区：[1]山东省淄博市中心医院,山东淄博255000

出　　处：《中外医疗》2009年第24期14-15,共2页China & Foreign Medical Treatment

摘　　要：目的探讨多指标联合诊断肺癌的价值及组合。方法采用蛋白芯片法检测12项肿瘤标志物;术前肺癌组126例,对照组120例。结果经SPSS软件的多元逐步回归法处理,12项指标中筛得肺癌联合诊断有价值的指标为CEA,NSE和铁蛋白。经组合判别的诊断效率较单项指标高。结论CEA,NSE和铁蛋白是肺癌联合诊断的理想指标。Objective To study the diagnose value of combined multi-markers in lung cancer.Methods 12 type tumor markers were detected by protein chip technology.126 cases were lung cancer,120 cases were control.The were analyzed by SPSS.Results CEA,Ferritin and NSE were good combine markers diagnosing lung cancer,the availability of CEA,Ferritin and NSE were better than single marker.Conclusion CEA,Ferritin and NSE were good combine markers in diagnosing lung cancer,CEA,Ferritin and NSE was the best combination.

关 键 词：肺癌 蛋白芯片 肿瘤标志物 

分 类 号：R734.2[医药卫生—肿瘤]