开道散合扶正和胃合剂治疗上消化道癌性狭窄疗效观察  

Clinical Observation of Kaidao Powder Combining with Fuzheng Hewei Mixture for the Treatment of Cancerous Stricture of Upper Digestive Tract

作　　者：胡萍萍[1] 金春晖[1] 戈晓兰[1] 

机构地区：[1]无锡市中医医院,江苏无锡214001

出　　处：《新中医》2009年第9期32-33,共2页New Chinese Medicine

摘　　要：目的:观察开道散合扶正和胃合剂治疗上消化道癌性狭窄的临床疗效。方法:对40例患者采用口服开道散、扶正和胃合剂联合胃镜下癌灶内注射5-氟脲嘧啶注射液及鸦胆子乳剂方法治疗上消化道癌性狭窄。结果:治疗后无瘤灶消失病例,34例患者肿瘤缩小达50%以上,完全缓解0例,部分缓解34例,稳定4例,进展2例,有效率为85.0%。治疗后患者吞咽困难有了较明显的改善,显效7例,有效31例,无效2例,总有效率95.0%。治疗后所有患者的卡氏评分均有所升高,与治疗前比较,差异有显著性意义(P<0.05),提示治疗后患者的生活质量有所改善。结论:开道散合扶正和胃合剂治疗上消化道癌性狭窄疗效满意,能使实体瘤缩小、吞咽困难改善、生活质量提高。Objective:To observe the therapeutic effect of Kaidao Powder(KP) combining with Fuzheng Hewei Mixture(FHM) for the treatment of cancerous stricture d upper digestive tract. Methods:Forty patients with ancerous stricture of upper digestive tract received oral use of KP and FHM,and received injection of 5 -fluorouracil and Yadanzi Emulsion into the cancer focus under gastroscope.Results:After treatment,none of the patients had the disappearance cancer focus, 34 patients had the reduction of cancer focus up to 50%.None of the patients was in complete remission, 34 patients(85.0%) were in partial remission,4(10.0%) were in stability,and 2 (5.0%) were in progress,the effective rate was 85.0%.Dysphagia was much relieved after treatment: 7(17.5%) patients were markedly effective,31(77.5%) were effective,2(5.0%) were ineffective,and the total effective rate was 95.0%.The Karnofsky score was increased in all of the patients(P<0.05 compared with that before treatment).Conclusion:KP combining with FHM is effective for the treatment of cancerous stricture of upper digestive tract,which can reduce the tumor mass,relieve dysphagia and improve the quality of life.

关 键 词：上消化道癌性狭窄 开道散 扶正和胃合剂 

分 类 号：R735[医药卫生—肿瘤]