去甲肾上腺素与多巴胺治疗肝肾综合征疗效对比分析  

Comparative analysis the effect of Noradrenaline and Dopamine in hepatorenal syndrome.

作　　者：江军[1] 范平[1] 陈仕祥[1] 丁雄芳[2] 

机构地区：[1]解放军第一一三医院感染科,浙江宁波315040 [2]宁波市第一医院药剂科,浙江宁波315010

出　　处：《临床肝胆病杂志》2009年第4期279-280,共2页Journal of Clinical Hepatology

摘　　要：目的观察去甲肾上腺素与多巴胺对肝肾综合征的治疗疗效。方法40例肝肾综合征患者随机分成2组,分别用去甲肾上腺素(nonadrenaline,NA)与多巴胺(Dopam ine,DM)进行治疗,观察它们在改善肾功能,增加尿量的疗效。结果NA组治疗后血肌酐、尿素氮均较治疗前明显降低(P<0.05),DM组治疗后日尿量较治疗前明显升高(P<0.05)。结论NA组效果优于DM组,NA能使患者肝肾综合征(HRS)得到逆转,NA对改善HRS患者预后有积极的作用。Objective To investigate and analysis the effect of Noradrenaline and Dopamine on treating hepatorenal syndrome （HRS）. Methods 40 cases with hepatorenal syndrome were randomly divided into noradrenaline （NA） group and dopamine （DM） group, The kidney function and urine volume were observed. Results The level of serum creatinine and blood urea nitrogen decreased signicantly after treatment in NA group （ P 〈 0. 05 ）, The volume of urine output increased significantly after treatment in DM group （ P 〈 0. 05 ）. Conclusion NA group has a better treatment effect than DM group. Noradrenaline might reverse HRS and improve prognosis of patients with HRS.

关 键 词：肝肾综合征 去甲肾上腺素 多巴胺 

分 类 号：R575.29[医药卫生—消化系统]