正畸牙齿移动过程中牙槽骨的Micro-CT形态学研究  

Morphological changes of alveolar bone during orthodontic tooth movement on Micro-CT

作　　者：庄丽[1] 孟宪莹 白玉兴[1] 

机构地区：[1]首都医科大学口腔医学院正畸科,北京100050 [2]北京朝阳医院

出　　处：《北京口腔医学》2009年第4期181-183,共3页Beijing Journal of Stomatology

基　　金：国家自然科学基金(10672109)

摘　　要：目的了解不同矫治力作用下牙槽骨骨小梁显微结构变化情况,探索正畸过程中牙槽骨骨小梁结构变化规律,为正畸临床提供指导。方法选择11周龄SD雄性大鼠22只,分别施加100g和30g矫治力,近中移动上颌第一磨牙建立实验动物模型。2周后处死动物,获得上颌第一磨牙及其周围牙槽骨。使用Skyscan 1172型Micro-CT扫描大鼠上颌牙槽骨骨小梁,计算骨小梁显微结构的各项参数并进行统计学分析。结果施加矫治力2周后,轻力组、重力组牙槽骨骨体积分数(BV/TV)都较对照组显著升高,重力组牙槽骨骨小梁间隙(Tb.Sp)比对照组明显减少(P<0.05),但重力组和轻力组之间没有显著性差别。结论在正畸矫治力产生的压应力作用下,牙槽骨进行相应的改建。Objective To examine the microstructure of alveolar trabecular bone during orthodontic tooth movement by Micro-CT. Methods The upper first molars of 22 SD rats were loaded with two different magnitude of forces for 2 weeks. The loaded teeth and the alveolar bone around the teeth were then taken off and analyzed for the structure of the alveolar trabecular bone. Results The BV/TV of 30 g group and 100 g group increased significantly compared to the control group,and Tb. Sp of 100 g group decreased significantly compared to the control （P 〈 0. 05 ） , but there was no significant difference between the 30g group and 100g group in Tb. Sp. Conclusion Pressure can result in alveolar bone rebuilding.

关 键 词：正畸 骨小梁 Micro—CT 形态学 

分 类 号：R783.5[医药卫生—口腔医学]