52例阿尔茨海默病患者血清硒、锌水平与患病关系的研究  

STUDY ON THE RELATIONSHIP BETWEEN THE LEVEL OF SERUM SELENIUM,ZINC AND ALZHEIMER'S DISEASE IN 52 PATIENTS

作　　者：熊丽萍[1] 黄河浪[1] 颜世铭 

机构地区：[1]江西南昌大学医学院,南昌330006 [2]南昌现代微量元素科学研究所

出　　处：《现代预防医学》2009年第15期2840-2840,2845,共2页Modern Preventive Medicine

基　　金：国家自然科学基金资助项目(30760214)

摘　　要：[目的]探讨硒、锌与阿尔茨海默病的关系。[方法]应用原子吸收分光光度计检测硒、锌。[结果]在社区内抽查2408人,确诊AD患者113人,总患病率为4.69%。AD患者血清锌值为57.42±13.79,显著低于对照(67.53±13.41,t=4.306,P=0.001)。患者血清硒值为2.10±1.01,也显著低于对照(3.01±1.09,t=3.094,P﹤0.05)。[结论]硒、锌是阿尔茨海默病保护因素。[Objective]In order to find out the relationship between Alzheimer＇s disease and zinc, selenium. [Methods] Detected on selenium, zinc with atomic absorption spectrophotometer. [Results] Among 2 408 spot checks in the com- munity, there were 113 patients diagnosed with AD, with a total prevalence rate of 4.69 percent. AD patients＇ serum zinc value was 57.42 ± 13.79, significantly lower than the control （67.53 ± 13.41, t = 4.306, P = 0.001） and whose serum selenium value was 2.10 ± 1.01, significantly lower than that of control （3.01 ± 1.09, t = 3.094, P﹤0.05）. [Conclusion] Selenium and zinc are the protective factors for Alzheimer＇s disease.

关 键 词：硒 锌 阿尔茨海默病 关系 

分 类 号：R749.16[医药卫生—神经病学与精神病学]