海洋生物多糖抗肿瘤作用机制的研究进展  

Progress in research of antitumor mechanisms of marine polysaccharides

作　　者：周庆峰[1] 李明月[2] 那广水[3] 李成伟[1] 

机构地区：[1]商丘师范学院生命科学系,河南商丘476000 [2]中国药科大学生命科学学院,江苏南京210009 [3]国家海洋环境监测中心,辽宁大连116023

出　　处：《中国药理学通报》2009年第8期995-997,共3页Chinese Pharmacological Bulletin

基　　金：河南省科技厅重点科技攻关资助项目(No092102310209);河南省教育厅自然科学基金资助项目(No2009B180021);商丘师范学院生物化学与分子生物学重点学科资助项目

摘　　要：多糖具有较强的免疫调节及抗肿瘤作用,已经成为肿瘤治疗的研究热点之一。目前,从海洋中获得了越来越多结构新颖、作用独特的活性多糖,有望成为肿瘤治疗中新的药物资源,该文通过对国内外相关文献进行检索,综合了国内外近年来的研究,对近年来海洋多糖的抗肿瘤作用机制的研究进展作一概述。polysaccharide has become a research focus in tumor therapy because of possessing positive immunomodulating and antitumor activities. At present, a series of polysaccharides with novel structures and unique function have been isolated from marine resources, which are potential choices for anti-tumor drugs. How-ever, few reviews are reported about the antitumor mechanism of marine polysaccharide, so the progress in research of antitumor mechanisms of marine polysaccharide are reviewed in this paper.

关 键 词：海洋 生物多糖 抗肿瘤 作用机制 细胞周期 凋亡 

分 类 号：R-05[医药卫生] R282.77