认知行为疗法并帕罗西汀治疗惊恐障碍疗效分析  

Effect Analysis on Cognitive Behavior Therapy for Panic Disorder

作　　者：余学[1] 赵福涛[1] 刘向阳[1] 孙群星[1] 

机构地区：[1]中国.河南省驻马店市精神病医院,463000

出　　处：《中国健康心理学杂志》2009年第8期901-902,共2页China Journal of Health Psychology

摘　　要：目的评价认知行为疗法并帕罗西汀治疗惊恐障碍的治疗效果。方法将符合中国精神障碍分类与诊断标准的69例惊恐障碍患者随机分为研究组(n=37)和对照组(n=32)。研究组给予认知行为并帕罗西汀治疗,对照组单用帕罗西汀治疗,疗程12周,在入组前和治疗2、4、8、12周末应用临床疗效标准和汉密尔顿焦虑量表(HAMA)评定疗效。完成该研究的60名参与者的数据纳入了结果分析。结果汉密顿焦虑量表总分研究组治疗2周末较治疗前有极显著性下降(t=5.56,P<0.01);对照组治疗4周末较治疗前有极显著性下降(t=4.27,P<0.01);治疗后2、4、8、12周末研究组疗效显著优于对照组。结论认知行为疗法并帕罗西汀治疗惊恐障碍效果优于单用帕罗西汀治疗。Objective To evaluate the curative effect of cognitive behavior therapy （CBT） combined paroxetine for panic disorder. Methods A total of 69 inpatients who met CCMD-3 for panic disorder were randomly assigned to study group （n=37） and control group （n=32）. Study group received CBT in addition to paroxetine,while control group received paroxetine only for 12 weeks. The curative effect was assessed with HAMA before and after treatment 2,4,8 and 12 weekends. For outcome analysis,dates from 60 participants were available who completed this study. Results The total score of HAMA in study group was significant lower than than before treatment at 2 weekend （t=5.56,P〈0.01）; so did in control group at 4 weekend （t=4.27,P〈0.01）. The therapeutic efficacy of CBT combined with paroxetine was significantly higher than that of control group after treatment 2,4,8 and 12 weekends. Conclusion It is suggest that CBT combined with paroxetine hold better effect for panic disorder than sole paroxetine.

关 键 词：认知行为疗法 惊恐障碍 帕罗西汀 汉密尔顿焦虑量表 

分 类 号：R749.7[医药卫生—神经病学与精神病学] R644[医药卫生—临床医学]