精神分裂症合并代谢综合征的调查  

A survey of metabolic syndrome in schizophrenia

作　　者：吕建宝[1] 王宁[1] 杨旭[1] 康燕霞[1] 加春彦[1] 赵晓彦[1] 刘艳红[1] 卞清涛[1] 

机构地区：[1]北京回龙观医院临床一科,100096

出　　处：《神经疾病与精神卫生》2009年第4期300-302,共3页Journal of Neuroscience and Mental Health

摘　　要：目的调查精神分裂症合并代谢综合征（metabolic syndrome，MS）的患病率及相关因素。方法对住院的210例精神分裂症患者进行MS调查和相关实验室指标测定，MS的诊断标准采用2004年中华医学会糖尿病分会标准。结果资料完整的精神分裂症住院患者210例；精神分裂症患者合并MS的患病率为18．9％，72．1％的患者至少有1项MS成分；MS组饮酒史阳性者比例显著高于非MS组（P〈0．05）；体重指数（BMI）与MS的发生直线相关（r=0．350，P〈0．01）。结论精神分裂症患者具有较高的MS发生风险，BMI是一项重要的预测指标，饮酒史是危险因素。Objective To assess the prevalence of metabolic syndrome （MS） in schizophrenia and MS related factors. Methods 210 patients with schizophrenia were enrolled and investigated in this study. The relative biochemical laboratory examinations were performed. The diagnosis of MS met the criteria of branch of diabetes mellitus of Chinese Medical Association. Results The overall prevalence of MS diagnosed according to the criteria was 18.9%, 72.1 % of schizophrenics had at least one MS factor, the rate of patients with drinking history in MS group was higher than that in Non--MS group. Body Mass Index （BMI） correlated significantly with MS （r = 0. 350, P 〈 0.01）. Conclusions This study showed that the prevalence of MS was high in patients with schizophrenia. BMI may be one of the predictable factors for MS. The history of drinking may be a risk factor of MS.

关 键 词：精神分裂症 代谢综合征 患病率 

分 类 号：R749.3[医药卫生—神经病学与精神病学] R589[医药卫生—临床医学]