Regio- and stereo-selective synthesis of multi-substituted 3-pyrrolines  

作　　者：Jian Feng Xu Peng Bin Li Lu Ling Wu Xian Huang 

机构地区：[1]Department of Chemistry, Zhejiang University (Campus Xixi), Hangzhou 310028, China [2]State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032, China

出　　处：《Chinese Chemical Letters》2009年第9期1015-1016,共2页中国化学快报（英文版）

基　　金：the National Natural Science Foundation of China(No.20672095);CAS Academician Foundation of Zhejiang Province for financial support

摘　　要：A regio- and stereo-selective synthesis of multi-substituted 3-pyrrolines has been developed. The multi-substituted 3-pyrrolines were synthesized in good yields by 1,3-dipolar cycloaddition of methyl 2-（phenylselanyl）acrylate with azomethine ylides, followed by N-acylation and oxidation-elimination of phenylseleno group. 2009 Xian Huang. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved.A regio- and stereo-selective synthesis of multi-substituted 3-pyrrolines has been developed. The multi-substituted 3-pyrrolines were synthesized in good yields by 1,3-dipolar cycloaddition of methyl 2-（phenylselanyl）acrylate with azomethine ylides, followed by N-acylation and oxidation-elimination of phenylseleno group. 2009 Xian Huang. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved.

关 键 词：3-Pyrrolines 1 3-Dipolar cycloaddition REGIOSELECTIVE STEREOSELECTIVE 

分 类 号：O625[理学—有机化学] TQ453.4[理学—化学]