急性缺氧对动物血液、肝、脑中酮体含量的影响  

EFFECT OF ACUTE HYPOXIA ON KETONE BODIES IN RAT BLOOD, LIVER AND BRAIN

作　　者：吴怀春[1] 吕永达[1] 王佩纲 

机构地区：[1]军事医学科学院卫生学环境医学研究所

出　　处：《解放军预防医学杂志》1998年第3期180-182,共3页Journal of Preventive Medicine of Chinese People's Liberation Army

摘　　要：为观察大鼠在不同海拔高度和不同缺氧时间血液、肝、脑组织酮体含量变化，大鼠分别在５０００ｍ、７０００ｍ、９０００ｍ模拟高度，每高度度均分别停留２、４和８ｈ。结果表明，在７０００ｍ高度停留２及４ｈ，以及在９０００ｍ高度停留２、４及８ｈ，血中酮体浓度显著高于海平时，而肝组织中酮体含量则显著地低于海平时，脑组织中酮体含量在上述３个模拟高度。To investigate the changes of ketone body contents in blood, liver and brain ,the rats were exposed to hypoxia at simulated altitudes of 5 000 m, 7 000 m, and 9 000 m for 2, 4, and 8 hours. The results showed that the concentration of blood ketone body was significantly increased at simulated altitudes of 7 000 m for 2 and 4 hours and 9 000 m for 2, 4, and 8 hours as compared with that at sea level. However the content of ketone body in liver was markedly decreased after exposure to hypoxia at simulated altitudes of 7 000 m for 2 and 4 hours and 9 000 m for 2, 4, and 8 hours. The content of ketone body in brain did not obviously changed at whichever simulated altitude.

关 键 词：缺氧 血液 肝 酮体 脑 

分 类 号：R364.4[医药卫生—病理学]