铜绿假单胞菌注射液在乳腺癌切除术后皮下积液中的临床应用  

Clinical application of piliated pseudomonas aeruginosa for breast cancer patients after operation with seroma formation

作　　者：马富懿[1] 王礼泉[1] 王昌亮[1] 林明臻[1] 

机构地区：[1]潍坊市人民医院肿瘤外科,山东潍坊261041

出　　处：《中华肿瘤防治杂志》2009年第14期1111-1112,1119,共3页Chinese Journal of Cancer Prevention and Treatment

摘　　要：为了探讨乳腺癌术后皮下积液不同处理办法间的差异,将乳腺癌术后皮下积液患者97例随机分为铜绿假单胞菌组(61例)和常规处理组(36例),铜绿假单胞菌组采用铜绿假单胞菌注射液局部皮下、残腔及腔周各注射1/3的量。常规处理组则行细针穿刺和置管引流,腔内注入四环素、泛影葡胺或50%葡萄糖等,比较两组患者积液消失的时间。铜绿假单胞菌组的创面愈合时间平均为9.836d,对照组为16.361d。初步研究结果提示,乳腺癌术后皮下积液局部应用铜绿假单胞菌注射液可明显减少皮下积液的产生,有利于创面愈合。The objective of this study was to explore the differences among different treatments used in seroma formation after operation for breast cancer patients. Ninty-seven patients who suffered seroma after breast cancer surgery were divided into two groups randomly, that were treated with the piliated pseudomonas aeruginosa （61 patients） and conventional treatments respectively （36 patients）. In the piliated pseudomonas aeruginosa group, the patients after operation with seroma formation were treated by injecting piliated pseudomonas aeruginosa subcutaneously to incomplete cavity and pericavity. In the conventional treatment group, the patients were treated by fine needle aspira tion, tube drain and injecting tetracycline, acetrizoic acid or 50% glucose into the incomplete cavity. Then the con crescence time of each group was compared, the average concrescence time of the piliated pseudomonas aeruginosa group was 9. 836 d, while the one of the control group was 16. 361 d. The piliated pseudomonas aeruginosa can obvi ously reduce the produce of seroma formation and accelerate the wound healing after operation for breast cancer patients.

关 键 词：乳腺肿瘤 铜绿假单胞菌 积液 

分 类 号：R737.9[医药卫生—肿瘤]