奥拉西坦治疗轻中型血管型痴呆患者记忆与智能障碍  

Oxiracetam in Treatment of Anamnesis and Aptitude Impediment in Patients with Mild to Medium Vascular Dementia

作　　者：谢仁兵 顾新红[1] 

机构地区：[1]江苏省如皋市人民医院,江苏如皋226500

出　　处：《临床医学工程》2009年第9期46-47,共2页Clinical Medicine & Engineering

摘　　要：目的评价奥拉西坦在治疗脑梗塞引发记忆或者智能障碍中的效果。方法将入选的患者,随机分为治疗组和对照组研究,其在年龄、性别、教育程度等方面,经t检验无显著性差异。对照组尼莫地平(片剂,20 mg/次,3次/d口服)治疗30 d。治疗组尼莫地平+奥拉西坦(胶囊,800 mg/次,3次/d口服)治疗30 d。结果对所有患者进行简易智能状态量表(MMSE)以及巴氏指数(BI)检查,结果经χ2检验量表分数测定,对照组与治疗组分数增加值,具有显著性差异。结论奥拉西坦治疗脑梗塞引发记忆或者智能障碍,对患者的认知功能、痴呆程度、日常生活能力,均有明显的改善。Objective To evaluate the effect of oxiracetam in treatment of impediment of anamnesis and aptitude caused by cerebral in farction. Methods The patients selected were randomly divided into treatment group and control group, with no significant difference in age, sex, education level, etc., by t test. Nimodipine control group （tablet, 20 mg / second, 3 times/d orally） for 30 d. Nimodipine treatment group ＋ oxiracetam （capsules, 800 mg / time, 3 times/d orally） for 30 d. Results For all patients checked with mini-mental state examination （MMSE） and Barthel Index （BI） and measured by the X^2 test scale scores in the control group and treatment group, the added scores had a significant dif ference. Conclusion Oxiracetam in treatment of impediment of anamnesis and aptitude caused by cerebral infarction has significantly im proved the cognitive function, the degree of dementia, activities of daily life of patients.

关 键 词：奥拉西坦 脑梗塞 记忆与智能障碍 

分 类 号：R749.13[医药卫生—神经病学与精神病学]