T淋巴细胞在缺血性脑损伤中的作用  

The of T-lymphocytes in ischemic brain injury

作　　者：李玲玲[1] 叶兰[1] 徐运[2] 

机构地区：[1]东南大学临床医学院,南京210009 [2]南京大学医学院附属鼓楼医院神经内科,210008

出　　处：《国际脑血管病杂志》2009年第8期636-640,共5页International Journal of Cerebrovascular Diseases

基　　金：国家自然科学基金（30470612）,江苏省科教兴卫工程医学重点人才项目（RC2007006）

摘　　要：缺血性脑损伤程度与卒中的病死率和致残率密切相关，如何最大程度地限制缺血性脑损伤，促进神经功能恢复，是当今神经科学领域十分关注的研究热点之一。大量研究表明，多种因素参与了缺血性脑损伤的病理过程。其中，T淋巴细胞介导的免疫炎症反应在缺血性脑损伤中的作用越来越受到关注，文章主要综述了T细胞在缺血性脑损伤中的作用。The severity of ischemic brain injury was closely associated with the mortality and disability of stroke. How to limit ischemic brain injury to the greatest extent and promote the recovery of neurological function is one of the most concerned hotspots at present in the field of neuroscience. A large number of studies have shown that a variety of factors involve in the pathological process of ischemic brain injury, in which, the role of T lymphocyte-mediated immune inflammatory response in ischemic brain injury has received increasing attention. This article mainly reviews the role of T cells in ischemic brain injury.

关 键 词：脑缺血 脑损伤 T淋巴细胞 

分 类 号：R743.3[医药卫生—神经病学与精神病学]