1-[5-(4-硝基苄基)-2H-四唑乙酰基]-4-芳酰氨基硫脲的合成  

Synthesis of 1-[5-(4-nitrobenzyl)-2H- tetrazol-2-acetyl]-4 aroylthiosemicarbazides

作　　者：孙乐[1] 王哨兵[1] 张艳[1] 张自义[1] 

机构地区：[1]兰州大学化学系应用有机国家重点实验室

出　　处：《兰州大学学报（自然科学版）》1998年第3期77-81,共5页Journal of Lanzhou University(Natural Sciences)

摘　　要：利用５－（４－硝基苄基）－２Ｈ－四唑－２－乙酰肼与芳酰基异硫氰酸酯在无水丙酮中反应，制得１０种新的－１－［５－（４－硝基苄基）－２Ｈ－四唑乙酰基］－４－芳酰氨基硫脲．所有化合物结构经元素分析、红外、１ＨＮＭＲ和质谱方法确认，生物活性正在进行中．Ten novel 1-[5-(4-nitrobenzyl)-2H- tetrazol-2-acetyl]-4 aroylthiosemicarbazides have been synthesized by the condensation of 5 (4 nitrobenzyl) 2H tetrazol 2 acylhydrazide with various aroylisothiocyanates. The structures of these compounds have been determined by elemental analysis, IR,, 1H NMR and MS, and their biological activities are now under testing.

关 键 词：芳酰氨基硫脲 2H-四唑 合成 乙酰基 

分 类 号：O623.54[理学—有机化学] O626.28[理学—化学]