盆腔动脉灌注化疗治疗中晚期宫颈癌的临床研究  

作　　者：王倩青[1] 赵慧玲[1] 许倩[1] 

机构地区：[1]新乡市中心医院妇瘤科,453003

出　　处：《当代医学》2009年第28期8-10,共3页Contemporary Medicine

摘　　要：目的探讨盆腔动脉灌注化疗治疗中晚期宫颈癌的疗效及临床意义。方法46例中晚期宫颈癌(Ⅱb期22例,Ⅲa～b期18例,Ⅳ期6例)行超选择髂内动脉化疗栓塞78次,观察并评定其疗效。结果近期疗效CR者9例(19.6%),PR29例(63.0%),CR+PR共38例(82.6%)。远期疗效1年生存共29例;3年生存共14例;5年生存共10例;7年生存共6例。结论介入超选择髂内动脉化疗栓塞是治疗中晚期宫颈癌的安全有效的方法。它能降低肿瘤细胞活性,提高生存率,在中晚期宫颈癌综合治疗中具有重要临床意义。objective To exlpore the therapeutic effect of pelvic intraarterial chemotherapy for advanced cervical carcinoma. Methods Forty-six patients with advanced cervical carcinoma（22 patients of stage Ⅱ b, 18 patients of stage Ⅲa-b,6 patients of stage Ⅳ） were chose and given internal iliac arterial chemoembolization for seventy-eight times,and then evaluate its efficacy. Results The overall response rate was 82.6%（38/46）.Nine patients had complete response（19.6%） and twenty-nine patients had partial response（63.0%） in one year after treatment; A total of 29 patients survival for one year, 14 patients survival for three years, 10 patients survival for five years,and 6 patients survival for seven years. Conclusion Internal iliac arterial chemoembolization for advanced cervical cancer is a safe and effective treatment method. It can reduce the activity of tumor cells and improve the survival rate.

关 键 词：宫颈肿瘤 介入治疗 髂内动脉 化疗栓塞 

分 类 号：R737.33[医药卫生—肿瘤] R737.310.5[医药卫生—临床医学]