经皮心包腔内置管化疗治疗恶性心包积液疗效观察  

Treatment of malignant pericardial effusion with chemotherapy through percutaneous intrapericardial intubation

作　　者：文洽先[1] 朱娅[1] 

机构地区：[1]无锡市第三人民医院,214041

出　　处：《中国肿瘤临床与康复》2009年第4期350-351,354,共3页Chinese Journal of Clinical Oncology and Rehabilitation

摘　　要：目的探讨和评价微创经皮心包腔内置管引流并注入化疗药物治疗恶性心包积液的效果。方法B超引导下，以心左缘浊音界内或剑突下为穿刺点，将中心静脉导管置入心包腔，放液干净后注入DDP30～40mg，IL-2100万U，Dx 5mg。结果心包腔置管化疗组与单纯心包抽液化疗组总有效率分别为80．0％和37．5％，差异具有显著性（P〈0．001）。结论心包腔内置管注药化疗治疗恶性心包积液，疗效佳，可迅速缓解心包填塞症状。Objective To study and evaluate the efficacy of microinvasive percutaneous intrapericardial intubation for drainage and injection of chemotherapeutic drug in treatment of malignant perieardial effusion. Method Under B-ultrasound guidance, a central vein catheter was inserted into the pefieardial cavity through the puncture point at the left border of heart dullness area or under the typhoid pro. After completely draining off the effusion, DDP 30-40 mg, IL-2 10 × 10^5 U and Dx 5 mg were injected. Results The overall effective rates of pericardial intubation chemotherapy group and simple pericardial drainage and chemotherapy group were 80. 0% and 37. 5% respectively, with significant difference （P 〈0. 001 ）. Conclusion The intrapericardial intubation and injection of chemotherapeutic drugs for treatment of maligant perieardial effusion has good therapeutic efficacy and can quickly relieve the symptoms of pericardial tamponade.

关 键 词：肿瘤 心包积液 化学疗法 

分 类 号：R730.5[医药卫生—肿瘤]