重庆市碘缺乏病高危地区重点人群碘营养状况调查与分析  

Investigation on and analysis of iodine nutritional of targeted population in the high-risk areas of iodine deficiency disorders in Chongqing

作　　者：李心术[1] 廖文芳[1] 谢军[1] 罗飞[1] 陈静[1] 周倩如[1] 

机构地区：[1]重庆市疾病预防控制中心地方病防治科,400042

出　　处：《中国地方病学杂志》2009年第5期531-533,共3页Chinese Jouranl of Endemiology

基　　金：重庆市科技攻关计划项目地方病预防与控制专项（CSTC,2008AB5054）

摘　　要：目的了解重庆市碘缺乏病高危地区重点人群碘营养状况，有针对性地提出防治对策。方法2007年4—5月，在重庆市城口、巫溪县的6个乡（镇），搜索所有的1997年1月1日以后出生的疑似地方性克汀病（地克病）儿童；在每个乡分别抽取8～10岁儿童200人，进行甲状腺检查、智商测定和采集尿样测定尿碘；在每乡抽取妇女（孕妇和哺乳期）40人，进行家庭食用盐碘测定和调查居民碘盐覆盖率及采集尿样测定尿碘。儿童甲状腺检查采用诊法和B超法，智商测定采用《中国瑞文联合型测验》（CRT-RC2）农村版，尿碘测定采用酸消化砷铈分光光度法，盐碘测定采用直接滴定法。结果城口、巫溪县乡镇医院报告疑似地克病6例，排除5例，另外1例为外地出生；8～10岁儿童甲状腺触诊法肿大率为9．58％（92／960），B超法肿大率为8．89％（65／731）；儿童平均智商（IQ）为103．32，尿碘中位数为319．15μg／L；妇女尿碘中位数为248．42μg／L，居民碘盐覆盖率为98．82％（336／340）。结论重庆市城口、巫溪县儿童碘营养状况良好，未发现当地出生的新发地克病患儿;8～10岁儿童甲状腺肿大率和尿碘，妇女尿碘和居民碘盐覆盖率达到基本消除碘缺乏病标准。Objective To investigate the iodine nutritional status of targeted population in the high-risk areas of iodine deficiency disorders in Chongqing, so as to provide scientific evidence for establishing prevention and remedial measures. Methods Six towns were selected in Chengkou and Wuxi Counties to found suspected dementia patients born after first Jan, 1997. Two hundred children aged 8 - 10 years were investigated in every town. The thyroid volume, intelligence quotient（IQ） and urinary iodine of the children were examined. Forty women （pregnant and nursing women） were investigated in every town. The iodine content of salt from their home was measured. The thyroid volume was examined by palpation and B-ultrasound. IQ was measured by combined Raven Test in China（CRT-RC2）. Urinary iodine was determined using the acid digest arsenic-cerium contacting method, and iodined salt was detected using direct titration method. Results Six suspected dementia patients were found in the local town hospital. Five cases were excluded. There was 1 case born in other place. The rates of goiter by palpation and B-ultrasound were 9.58% （92/960） and 8.89% （65/731）, respectively. The median of urinary iodine of children and women was 319.15 μg/L and 248.42 μg/L, respectively. The mean of IQ of the children was 103.32. The coverage rate of iodine salt from residents was 98.82%（336/340）. Conclusions The iodine nutrition of children was good and there is no newly occurred cretinism in Chengkou and Wuxi Counties. Goiter rate and median of urinary iodine aged 8 -10 years and of women, coverage rate of iodine salt from resident has meet the standard set for basieal elimination iodine deficiency disorders.

关 键 词：碘 缺乏症 儿童 妇女 甲状腺肿 地方性 智商 

分 类 号：R686[医药卫生—骨科学]