头孢菌素C发酵液可压缩性及膜分离的工艺研究  

Research on the Compressibility of the Cephalosporin C Fermentation Broth

作　　者：周天舒[1] 李杰[1] 秘彦坤 张晓艳[1] 

机构地区：[1]石药集团河北中润制药有限公司,河北石家庄050041

出　　处：《广州化工》2009年第6期128-129,共2页GuangZhou Chemical Industry

摘　　要：研究头C发酵液，确定头C发酵液具有一定的可压缩性，可压缩性指数在0．30～0．45之间。提出有效透膜压差的概念，认为膜通量与有效透膜压差成正比，对膜通量分析有积极作用。进一步探讨发酵液可压缩性对膜分离的影响，得出结论：可压缩性指数越小，有效透膜压差和透过通量越大，越有利于膜分离过程。Through studying cephalosporin C broth, it was confirmed that cephalosporin C broth was compressible and the value of the compressibility of its cake ranged from 0.30 - 0.45. A new concept of the effectual pressure drop of transferring membrane （ △ Pe ） was raised and we thinked the flux was proportional to △ Pe. The effect of the compressibility on membrane separation studied , we drew the conclusion that the decrease of the compressibility and the viscosity was favourable to APe and flux.

关 键 词：头孢菌素C 发酵液 可压缩性 

分 类 号：TQ028.8[化学工程] O213[理学—概率论与数理统计]