囊状动脉瘤血流动力学的DSA、彩色多普勒与病理的实验研究  

Heodynamicn study on experimental saccular aneurysm with DSA、color Doppler flow imaging and patholoy

作　　者：李文彬[1] 沈天真[2] 陈星荣[2] 黄祥龙[2] 冯晓源[2] 汪守中[1] 袁伟[3] 李建伟[3] 华秀云[4] 张福麟[5] 

机构地区：[1]上海市第一人民医院放射科,200080 [2]上海医科大学附属华山医院放射科,200080 [3]上海医科大学附属华山医院显微外科实验室,200080 [4]上海医科大学附属华山医院超声室,200080 [5]上海医科大学附属华山医院病理科,200080

出　　处：《中华放射学杂志》1998年第9期627-631,共5页Chinese Journal of Radiology

摘　　要：目的探讨囊状动脉瘤的血流动力学与动脉瘤生长、血栓形成或破裂之间可能的相互关系。方法用“静脉囊镶嵌法”将18只犬制成三种类型（单侧型、分叉型和末梢型）颈总动脉囊状动脉瘤模型。术后2、4周分别进行DSA、彩色多普勒检查，然后将犬处死进行病理观察。结果DSA、彩色多普勒能显示动脉瘤的位置、形态、类型，瘤体内血液循环状态。DSA、彩色多普勒显示动脉瘤的远侧缘、顶部、近侧缘为层流，瘤腔为湍流。三种类型动脉瘤模型既有相同的血流动力学特征，又有各自的特点。第4周时动脉瘤颈部、顶部、瘤内有血栓形成。结论动脉瘤的血流动力学直接影响动脉瘤的生长、血栓形成、破裂。Purpose To study saccular aneurysm hemedynamics with DSA, color Doppler flow imaging and pathology. Methods Eighteen experimental canine carotid aneurysms (6 lateral, 6 bifurcation, and 6 terminal) were constructed and examined with DSA and color Doppler (ATL Ultramark 9) in the 2nd and 4th week after the surgical procedure. The dogs were killed for pathologic study following completion of the DSA and color Doppler exam. Results DSA and color Doppler were capable not only of showing the location, morphology, type of experimental aneurysms, but also the intraaneuryslmal flow characteristics. At the distal side, the fundus, and the proximal side of the aneurysms. blood flow was laminar. but at the central region was turbulent flow. Besides, three types of aneurysms had different hemodynamic flow characteristics. There was thormbosis at the neck, fundus and in the cavity of the anelnysms in the 4th week. Conclusion DSA, color Doppler and pathological studies can further our understanding about the hemodynamic factors which can all be directly related to the powth. thrombosis or rupture of saccular anelnysms.

关 键 词：动脉瘤 血液动力学 DSA 病理学 彩色多普勒 

分 类 号：R732.210.4[医药卫生—肿瘤] R730.4[医药卫生—临床医学]