人胃腺癌组织的自体荧光光谱特性  

Characteristics of autofluorescence spectrum for human gastric adenocarcinoma tissue

作　　者：王娟[1] 何博华[2] 魏华江[3] 李力波[4] 旷焱平[1] 

机构地区：[1]广东药学院护理学院,广东广州510310 [2]广东药学院外科教研室,广东广州510310 [3]华南师范大学激光生命研究所,广东广州510631 [4]广东药学院第一附属医院胃肠外科,广东广州510080

出　　处：《现代肿瘤医学》2009年第10期1904-1906,共3页Journal of Modern Oncology

基　　金：广东省自然科学基金资助项目(编号:06032270);广东省医学科学基金资助项目(编号:A2006309)

摘　　要：目的:探讨人胃腺癌组织的自体荧光光谱特性。方法:测定26例胃腺癌标本肿瘤及非肿瘤区域的组织自体荧光光谱。结果:人胃腺癌组织自体荧光光谱与非肿瘤胃壁组织自体荧光光谱明显不同,人胃腺癌组织自体荧光光谱的峰值明显低于非肿瘤胃壁组织;用波长为360nm、390nm激光激发的人胃腺癌组织自体荧光光谱出现双峰。结论:用激光激发的自体荧光光谱可有效识别人胃腺癌组织与非肿瘤胃壁组织。Objective：To investigate the characteristics of autofluorescence spectrum for human gastric adenocarcinoma tissue. Methods：Autofluorescenee spectrum for gastric wall tissue were mensurated which gotten from tumorous region and non - tumorous region of 26 specimen of human gastric adenocareinoma. Results ： Autofluoreseence spectrums for gastric adenoeareinoma were different from that for non - tumorous gastric wall, the peak value of autofluorescenee spectrum for gastric adenocarcinoma was lower remarkably than for non - tumorous gastric wall. Double peak value presented in autofluorescence spectrum excitated by 360nm and 390nm wavelength laser for gastric adenoearcinoma. Conclusion：Autofluorescence spectrum excitated by laser can distinguish gastric adenocarcinoma tissue from non- tumorous gastric wall tissue effectively.

关 键 词：胃腺癌 自体荧光 激发波长 峰值 

分 类 号：R735.2[医药卫生—肿瘤]