苯酚在兽医生物制品检测中的应用  

Application of Phenol in Detection of the Antibody Titers of the Oil Emulsion and the Yolk Antibody

作　　者：常维山[1] 牛钟相[1] 朱瑞良[1] 柴家前[1] 唐珂心[1] 徐海花[1] 

机构地区：[1]山东农业大学

出　　处：《中国兽药杂志》1998年第3期14-15,共2页Chinese Journal of Veterinary Drug

摘　　要：作者们发现可以用低浓度苯酚作为破乳剂将油乳剂疫苗中水相分离出来，利用后者在体外进行免疫学测定。应用这个方法发现市售减蛋综合症疫苗中的血凝价为２１０，市售卵黄抗体中新城疫病毒血凝抑制价和抗法氏囊病病毒抗体价分别为２７～２９和２５～２７。The authors found that 2% phenol may be used as a demulsifier to separate the water phase out from the oil emusion vaccine and then using the water phase for immunological assay in vitro. With this method they demonstrated the titer of haemagglutinin in commercial EDS 76 vaccine was 2 10 , the haemagglutination inhibition titer for Newcastle virus and the titer of antibody agaist the infectious bursa disease virus in commercial yolk antibodies preparation were 2 7 ￣2 9 and 2 5 ￣2 7 respectively.

关 键 词：苯酚 兽药 生物制品 质量监测 

分 类 号：TQ460.7[化学工程—制药化工]