鼻咽癌高癌家系成员中医体质特征调查  

An Investigation of Physical Characteristics of Family Members in High-risk Nasopharyngeal Carcinoma Pedigree

作　　者：陈舒华[1] 田道法[2] 张继平[1] 成细华[2] 何迎春[2] 文凤妮[1] 周少雄[1] 陈闽琪[1] 江浩[1] 

机构地区：[1]佛山市第二人民医院,广东佛山528000 [2]湖南中医药大学中西医结合学院,湖南长沙410007

出　　处：《新中医》2009年第10期30-32,共3页New Chinese Medicine

基　　金：国家自然科学基金(编号:30572408;30271678);湖南省自然科学基金(编号:07JJ6041);广东省中医药局课题(编号:2050002)

摘　　要：目的:观察鼻咽癌高癌家系成员中医体质特征。方法:建立中医体质证候分类标准,分别调查鼻咽癌高癌家系核心成员、鼻咽癌高癌家系鼻咽癌患者的中医体质类型,并以散发性鼻咽癌患者(外对照组)及高癌家系已婚核心成员配偶(内对照组)进行中医病理体质的对照研究。结果:鼻咽癌高癌家系核心成员中医体质证候类型主要表现为正常质和气虚质,而内对照组成员则多表现为正常质,高癌家系鼻咽癌患者多表现为气虚质、失调热质和复合质,散发性鼻咽癌患者多表现为气虚质和复合质,后三者各组间比较,差异有显著性或非常显著性意义(P<0.05,P<0.01)。而将高癌家系核心成员中医体质类型与外对照组比较,差异无显著性意义(P>0.05)。51例高癌家系核心成员中,共有复合质7例,其中虚热质4例,虚湿质、湿热质、虚热瘀质各1例;而内对照组成员则未见复合质者。高癌家系鼻咽癌患者17例中,共有复合质7例,其中虚热质1例,虚湿质2例,湿热质3例,虚热瘀质1例,与高癌家系核心成员比较,差异无显著性意义(P>0.05)。外对照组成员34例中,有复合质6例,其中虚湿质3例,虚寒质1例,湿热质2例,与高癌家系核心成员及高癌家系鼻咽癌患者比较,差异无显著性意义(P>0.05)。体质证候积分高癌家系核心成员与内对照组成员比较,气虚质积分差异有非常显著性意义(P<0.01),失调瘀质积分差异有显著性意义(P<0.05)。高癌家系核心成员与高癌家系鼻咽癌患者比较,气虚质积分、失调瘀质积分差异有非常显著性意义(P<0.01),失调寒质积分比较,差异有显著性意义(P<0.05)。高癌家系核心成员与外对照组成员比较,失调寒质积分及失调瘀质积分,差异有非常显著性意义(P<0.01),失调湿质积分,差异有显著性意义(P<0.05)。结论:鼻咽癌高癌家系核心成员的中医体质类型中,除正常质外,病理体质主要表现为气虚质和复合Objective:To investigate the physical characteristics of family members in high-risk nasopharyngeal carcinoma pedigree.Methods:Criteria for physical syndromes were established. Physical types of the core members and nasopharyngeal carcinoma patients in high - risk nasopharyngeal carcinoma pedigree were investigated,and were compared with those of sporadic nasopharyngeal carcinoma patients(external control group) as well as the spouses of the core members in high-risk nasopharyngeal carcinoma pedigree(internal control group).Results:The simple physical types presented as normal constitution or Qi deficiency constitution in the core members of high - risk nasopharyngeal carcinoma pedigree,as normal constitution in internal control group,as Qi deficiency constitution,disordered heat constitution or complex constitution in nasopharyngeal carcinoma patients,and as Qi deficiency constitution or complex constitution in external control group(P<0.05 or P<0.01 compared with other groups).The composite physical types presented as complex constitution in 7 of 51 core members of high-risk nasopharyngeal carcinoma pedigree, deficiency heat constitution in 4,and deficiency damp constitution,damp heat constitution and deficiency - heat stasis constitution in one member respectively.No one was shown as complex constitution in the internal control group.In 17 nasopharyngeal carcinoma patients,7 had the complex constitution,1 had deficiency heat constitution,2 had deficiency damp constitution,3 had damp heat constitution and 1 had deficiency - heat stasis constitution,the difference being insignificant as compared with the core members of high - risk nasopharyngeal carcinoma pedigree(P>0.05).In 34 members of the external control group,the composite physical types presented as complex constitution in 6(deficiency heat constitution in 3,deficiency cold constitution in 1 and damp heat constitution in 2),the difference being insignificant as compared with those in the core members and nasopharyngeal carcinoma patients(P>0.05).The diff

关 键 词：鼻咽癌 高癌家系 中医体质类型 病因学 

分 类 号：R739.63[医药卫生—肿瘤]