山西省阳城县5073例上消化道内窥镜筛查结果分析  

Analysis on 5073 persons of upper gastrointestinal endoscopic screening in Yangcheng county Shanxi province

作　　者：王新正[1] 张永贞[2] 元芳梅[1] 王芳[1] 刘宽荣[1] 

机构地区：[1]山西省阳城县肿瘤医院肿瘤研究所科研办,048100 [2]山西省肿瘤研究所流行病室

出　　处：《肿瘤研究与临床》2009年第9期641-642,648,共3页Cancer Research and Clinic

基　　金：中央财政转移支付国家食管癌早诊早治项目

摘　　要：目的总结阳城县食管癌早诊早治项目内窥镜筛查情况和早期诊断结果。方法对5073例应用内窥镜检查＋碘染色＋指示性活组织检查及贲门脊根部定点活组织检查的普查资料进行分析。结果参加筛查的男女比为0．99：1，两组差异无统计学意义（P〉0．05）；不典型增生和癌的检出率男性明显高于女性（P〈0．01）；食管、贲门、胃的早期诊断率{早期诊断病例[重度不典型增生和（或）原位癌、黏膜内癌1／重度不典型增生和（或）原位癌以上病例）分别为73．33％、71．88％、44．44％。结论在食管癌高发区应用内窥镜检查＋碘染色＋指示性活组织检查可提高食管癌癌前病变的检出率，同时要重视对早期贲门癌的诊断，建议食管癌高发区常规内窥镜检查时应做碘染色＋指示性活组织检查和对贲门脊根部的定点活组织检查，以提高癌前病变的检出率。Objective To summarize endoscopic screening results of early detection and treatment of esophageal cancer in Yangcheng County, and to improve detection rate of precancerous lesions. Methods Analyze 5073 examples who were checked by endoscopy and iodine dyeing and cardia ridge root biopsy. Results Sex rate （male to female） was 0.99：1, there were statistics significant difference between two group （P 〉0.05）; male＇s detection rate of dysplasia and cancer was obvious higher than female＇ s （P 〈0.01）; The early detection rate of esophagus, cardia, stomach was 73.33 %, 71.88 %, 44.44 % respectively. Conclusion To use endoscopy and iodine dyeing and cardie ridge root biopsy can increase the detection rate of precancerous lesions in esophageal cancer high risk region.

关 键 词：食管肿瘤 胃肿瘤 细胞增生 内窥镜检查 消化系统 染色与标记 活组织检查 

分 类 号：R57[医药卫生—消化系统] R735.1[医药卫生—内科学]