Cytomegalovirus enteritis mimicking Crohn's disease in a lupus nephritis patient:A case report  

作　　者：Faisal Nazir Khan Vinod Prasad Michael David Klein 

机构地区：[1]Department of Nephrology,Westchester Medical Center,New York Medical College [2]Clinical Medicine,Department of Nephrology,Westchester Medical Center,New York Medical College

出　　处：《World Journal of Gastroenterology》2009年第34期4327-4330,共4页世界胃肠病学杂志（英文版）

摘　　要：Cytomegalovirus(CMV)infection of the gastrointestinal (GI)tract has been reported in both immunocompetent and,more frequently,in immunocompromised patients.We describe a case of a 19-year-old male who developed CMV infection of the terminal ileum while receiving immunosuppression for lupus nephritis. This was a distinctly unusual site of infection which clinically mimicked Crohn's ileitis.We note that reports of terminal ileal CMV infection have been infrequent. Despite a complicated hospital course,ganciclovir therapy was effective in resolving his symptoms and normalizing his ileal mucosa.This report highlights the importance of accurate histological diagnosis and clinical follow-up of lupus patients with GI symptoms undergoing intense immunosuppression.Cytomegalovirus （CMV） infection of the gastrointestinal （GI） tract has been reported in both immunocompetent and, more frequently, in immunocompromised patients. We describe a case of a 19-year-old male who developed CMV infection of the terminal ileum while receiving immunosuppression for lupus nephritis. This was a distinctly unusual site of infection which clinically mimicked Crohn＇s ileitis. We note that reports of terminal ileal CMV infection have been infrequent. Despite a complicated hospital course, ganciclovir therapy was effective in resolving his symptoms and normalizing his ileal mucosa. This report highlights the importance of accurate histological diagnosis and clinical follow-up of lupus patients with GI symptoms undergoing intense immunosuppression.

关 键 词：CYTOMEGALOVIRUS ENTERITIS Lupus nephritis Terminal ileitis 

分 类 号：R574[医药卫生—消化系统] R692.3[医药卫生—内科学]