山楂降血脂作用有效部位的研究  

Research of Blood-lipid Lowering Components of Hawthorn

作　　者：唐世英[1] 胡桂才[2] 李来[1] 杨凤国[1] 

机构地区：[1]承德医学院,河北承德067000 [2]承德医学院附属医院,河北承德067000

出　　处：《云南中医学院学报》2009年第5期43-45,共3页Journal of Yunnan University of Traditional Chinese Medicine

摘　　要：目的:探讨山楂降脂作用及其有效部位。方法:把山楂分离成总黄酮、残渣、浸膏3个组分,每种组分取4个剂量水平。16只金黄地鼠按直接设计方案进行实验。每周测定血浆总胆固醇、甘油三酯。结果:山楂总黄酮、残渣及其交互作用与TC、TG呈显著性负相关。结论:总黄酮是山楂降脂作用的主要成分,残渣可加强总黄酮降TG的作用。Objective： To investigate the blood lipid decreasing components of hawthorn. Methods： Hawthorn was separated into 3 components： Flavonoids （F）, Wasted （W） and Plaster （P） and 4 dosage levels in each. Experiment was arranged on the basis of Random Design using 16 male golden hamsters. TC and TG were measured once a week. Results： F, W and the interaction between them significantly decrease blood TC, TG. The best effective dosage is 0. 15mg/kg. wt. Conclusion： Flavonoids is the main effective ingredient of hawthorn on blood TC, TG. W. improve the effects of F on blood TG.

关 键 词：山楂 黄酮 胆固醇 甘油三酯 活性部位 

分 类 号：R285.5[医药卫生—中药学]