肺癌脑转移瘤64例适形放射治疗的疗效分析  

Three-dimensional Conformal Radiation Therapy for Brain Metastatic Tumors from Lung Cancer:Efficacy of 64 Cases

作　　者：刘杰[1] 王培合[1] 刘洪明[1] 

机构地区：[1]山东省潍坊市人民医院放疗科,山东潍坊261041

出　　处：《中国现代医生》2009年第26期52-53,共2页China Modern Doctor

摘　　要：目的探讨肺癌脑转移瘤患者采用适形放射治疗的疗效和毒副作用。方法对64例肺癌脑转移瘤患者先行全脑对穿放疗DT40GY,2GY/次,5次/周,再对脑转移瘤行三维适形放射治疗加量DT10-15GY,2GY/次,5次/周。结果放疗后复查脑CT或MRI示:完全缓解(CR)为43.8%%,部分缓解(PR)35.9%,无变化(NC)为15.6%,进展(PD)为4.7%。结论肺癌脑转移瘤患者给予适形放射治疗,能明显地提高肿瘤局部控制率,改善生活质量,延长生存期。Objective To study the efficacy and adverse effects of three-dimensional conformal radiation therapy（3DCRT） for patients of brain metastatic tumors from lung cancer. Methods Sixty-four cases of brain metastatic tumors from lung cancer were given 3DCRT. At first the whole brain was given radiation therapy of DT 40Gy（2Gy per time and five times per week）. Then metastatic tumors were given 3DCRT with the volume up to DT 10-15Gy（2Gy per time and five times per week）. Results The CT/MRI scanning images after radiotherapy showed that the complete tumor regression rate（CR）, partial tumor regression rate（PR）and no change rate（NC）were 43.8%, 35.9% and 15.6%,respectively. And the rate of progress disease （PD） was 4.7%. Conclusion 3DCRT for brain metastatic tumors from lung cancer can impro,~e the local control rate and prolong the survival time with few adverse effects.

关 键 词：肺癌 脑转移瘤 适形放疗 疗效 

分 类 号：R730.55[医药卫生—肿瘤]