纳米材料在电化学生物传感器中的应用进展  

Proceedings of nanomaterials applied in electrochemical biosensors

作　　者：游春苹[1,2] 吴正钧[1] 王荫榆[1] 孔继烈[2] 刘宝红[2] 郭本恒[1] 

机构地区：[1]光明乳业股份有限公司技术中心,上海200436 [2]复旦大学化学系,上海200433

出　　处：《化学传感器》2009年第3期1-7,共7页Chemical Sensors

基　　金：上海市国内科技合作项目(09395811500)

摘　　要：生物传感技术结合了信息技术与生物技术,涉及化学、生物学、物理学以及电子学等交叉学科,在医药工业、食品检测和环境保护等诸多领域有着广阔的应用前景。其中电化学生物传感器以其高选择性、高灵敏度、高检测速度和易于微型化以及便于在线监测等特点得到广泛研究和应用。其研制过程中的一个关键因素是生物分子的固定化。纳米技术的兴起为此带来无穷想象和诸多可能。近年来,越来越多的纳米材料如纳米颗粒、碳纳米管、纳米多孔材料和介孔材料等,被用于生物组分的固定,在保持固定化生物组分活性的同时又促进有效的电子转移。按照结构的不同类别,综述了近十年来纳米材料在电化学生物传感器方面的研究和应用进展。Biosensors, combining informatics and biotechnotogy, as an interdisciplinary frontier related to chemistry, biology, physics and electronics, will have broad applications in clinical medicine, food inspection and environment protection. Among them, electrochemical biosensors have been extensively studied and applied, due to the high selectivity, high sensitivity, fast responses and advantages in miniaturization and online detection. A key factor in biosensor development is the immobilization of biomolecules. The progress in nanotechnology brought infinite imaginations and great potentials. Recently, nanomaterials such as nanoparticles, carbon nanotubes, nanoporous materials and mesoporous materials have been increasingly employed to immobilize biocomponents, retaining their bioactivities and meanwhile promoting the effective electron-transfer. This paper reviews the proceedings during the last ten years of nanomaterials with different structures applied in electrochemical biosensors.

关 键 词：纳米材料 电分析 生物传感器 电化学 生物分子 蛋白质 

分 类 号：TB383.1[一般工业技术—材料科学与工程]