腺苷蛋氨酸治疗药物性肝病33例  

Ademetionine therapy in patients with drug induced liver disease clinical study of 33 cases

作　　者：邵景[1] 蒲利华[2] 

机构地区：[1]西安市第一医院,西安710002 [2]西安市儿童医院

出　　处：《陕西医学杂志》2009年第10期1376-1377,共2页Shaanxi Medical Journal

摘　　要：目的:探讨腺苷蛋氨酸(商品名思美泰)对药物性肝病(DILD)的治疗效果。方法:将65例药物性肝病患者随机分为治疗组和对照组,治疗组在对照组用药的基础上加用腺苷蛋氨酸(思美泰)治疗,比较两组的疗效。结果:治疗组较对照组总有效率无显著性差异(P>0.05),但显效率较对照组有显著性差异(P<0.05)。结论:腺苷蛋氨酸对胆汁淤积型和混合型药物性肝病效果较好,早期使用可以加快肝细胞功能恢复。Objective：To assess the efficacy of ademetionine in the treatment of drug induced liver disease （DILD）. Methods ：The 65 patients with DILD were randomly divided into the treatment group and the control group. The treatment of both groups were the same except that adimetionine was added in the treatment group. Then the effect was observed. Results ：The total effective rates of the two groups showed no significant difference （P〉0.05）, but the rate of obvious improvement of the treatment group was higher than that in the control group（P〈0.05）. Conclusion：Adimetionine has a good effect in the treatment of cholestatie or mixed DILD. The early use of adimetionine can promote the recovery of liver ceil functions.

关 键 词：肝炎 慢性 药物性/药物疗法 S-腺苷甲硫氨酸/治疗应用 对比研究 

分 类 号：R575[医药卫生—消化系统] R512.605[医药卫生—内科学]