4957例消化性溃疡临床与胃镜分析  

The Clinical and Endoscopic Analysis of 4957 Cases of Peptic Ulcer Diseases

作　　者：叶强[1] 黄梅芳[1] 施先艳[1] 夏冰[1] 

机构地区：[1]武汉大学中南医院消化内科,武汉430071

出　　处：《临床消化病杂志》2009年第5期275-277,共3页Chinese Journal of Clinical Gastroenterology

摘　　要：目的了解消化性溃疡胃镜检出率,并对疾病相关因素及其并发症、癌前病变进行分析。方法对2002～2007年在我院经胃镜检查确诊为消化性溃疡患者的病史及胃镜资料结果进行回顾性分析。结果(1)本组资料消化性溃疡患者中幽门螺杆菌(Hp)阳性率为56.41%,阴性率为41.82%。Hp阳性者以41～50岁年龄组最多见,少见于20岁以下和80岁以上年龄组。(2)我科5年来消化性溃疡患者中并发出血112例(2.26%),梗阻62例(1.25%),癌变108例(2.18%),未发现穿孔患者。(3)消化性溃疡患者中取胃黏膜活检751例,占15.51%,其中腺体萎缩23例,上皮内瘤变136例,肠上皮化生35例,上皮内瘤变并肠上皮化生20例。结论消化性溃疡是多发常见病,消化性溃疡Hp感染率较高(56.4%),应重视消化性溃疡常见并发症,常规镜下活检与病理诊断相结合有助于提高早期癌变诊断率。Objective To investigate peptic ulcer prevalence in hospital based study by gastroseopy in our hospital, and analyze peptic ulcers related factors and complieations and precancerous lesions. Methods Review case history records and endoscopy records of peptic ulcer diseases by retrospective study during 2002 - 2007 in our hospital. Results （ 1 ） The helicobacter pylori（Hp） positive rate is 56. 41% in patients with peptic ulcers,the negative rate of which is 41.82%. The most common age group of Hp infection is 41 to 50, and rare under the age of 20 or above 80 years old. （2）For 5 years, the peptic ulcer with bleeding is 112 cases （2. 26% ） , and 62 cases of obstruction（ 1.25 % ） , 108 cases of cancer（2. 18% ） and found no cases of perforated patients ; （ 3 ） Biopsies from patients with peptic ulcer in 751 cases （ 15.15 % ） , with 23 cases of glandular atrophy, intraepithelial neoplasia is 136,35 cases of intestinal metaplasia, intraepithelial Neoplasia and intestinal metaplasia is 20. Conclusion Peptic ulcer is the common diseases and the Hp infection of which is high（56.4% ）. We should attach importance to peptic ulcer complications, conventional endoscopic diagnosis combining biopsy will help to improve early diagnosis of cancer.

关 键 词：消化性溃疡 胃镜检查 病理诊断 幽门螺杆菌 

分 类 号：R573.1[医药卫生—消化系统]