画钟测验的错误类型对轻度认知障碍患者和健康老年人的鉴别诊断作用  

Differential Diagostic Value of the Clock Drawing Test for Identifying the Mild Cognition Impairment from Normal Ageing Controls

作　　者：赵圣杰[1] 赵永波[1] 郭春妮[1] 王铭琴[1] 

机构地区：[1]上海交通大学附属第一人民医院神经内科,上海200080

出　　处：《中国神经免疫学和神经病学杂志》2009年第5期366-369,共4页Chinese Journal of Neuroimmunology and Neurology

基　　金：上海市市级医院新兴前沿技术联合攻关基金资助项目(SHDC12006108);上海市科委基础研究重大基金资助项目(07DJ14005);中国博士后科学基金资助项目(20060390635)

摘　　要：目的探讨画钟测验(CDT)的错误类型鉴别轻度认知障碍患者和健康老年人的敏感度和特异度。方法轻度认知障碍(MCI)患者88例,健康老年对照者100名。由神经心理评估医师独立盲法检测CDT,采用Mendez等、Rouleau等和Freund等3种方法进行评分和划分CDT的错误类型,并进行简易精神状态(MMSE)及其他量表检测。计算CDT的错误类型鉴别MCI患者和健康对照的敏感度和特异度。结果 Rouleau等评分方法无法对MCI患者和健康对照者进行有效鉴别。Ⅰ、Ⅲ、Ⅴ、Ⅶ类错误可用于MCI在健康人群中的筛查,其特异度和敏感度分别为75%和77%。结论 CDT的错误类型可用于初步快速鉴别MCI患者和健康老年人。Objective To determine the validity of the clock drawing test （CDT） in differentiating mild cognition impairment from normal ageing controls. Methods 88 mild cognition impairment patients, 100 normal control subjects were comprehensively evaluated with mini-mental state examination （MMSE） and other tests. CDT was blindly scored by independent clinical psychclogists according to Mendez, Rouleau, Freund method. The sensitivities and specificities of the CDT measures for identifying mild cognition impairment from normal controls were calculated. Results Eleven errors were significantly associated with mild cognition impairment subjects, of which Ⅰ, Ⅲ, Ⅴ , Ⅶ are useful in discriminating mild cognition impairment from normal aging. Sensitivity and specificity were found to be 77% and 75%, respectively. Conclusions Clock-drawing errors are useful in discriminating mild cognition impairment from normal aging.

关 键 词：画钟测验错误类型 轻度认知障碍 鉴别诊断 

分 类 号：R749.16[医药卫生—神经病学与精神病学]