龙眼核的化学成分研究  

Studies on the Chemical Constituents from the Longan Seeds

作　　者：李雪华[1] 吴妮妮[1] 李福森[1] 黄燕军[1] 龙盛京[1] 

机构地区：[1]广西医科大学药学院,南宁530021

出　　处：《华中科技大学学报（医学版）》2009年第4期524-526,共3页Acta Medicinae Universitatis Scientiae et Technologiae Huazhong

基　　金：广西壮族自治区自然科学基金资助项目(No.0448050)

摘　　要：目的对龙眼核的化学成分进行分离并对其结构进行分析。方法通过溶剂提取、硅胶柱层析和重结晶等方法,分离提取龙眼核中的化学成分,根据波谱学技术(IR、1H-NMR、13C-NMR和MS)和化合物的理化性质进行结构鉴定。结果共纯化得到6个化合物。鉴定了其中的4个化合物,分别为:二十五烷(pentacosane,Ⅰ)、豆甾醇(stigmaster-ol,Ⅱ)、双(5-甲酰基糠基)醚[bis(5-formylfurfuryl)ether,Ⅲ]、没食子酸乙酯(ethyl gallate,Ⅳ)。结论二十五烷(pen-tacosane)、豆甾醇(stigmasterol)、双(5-甲酰基糠基)醚[bis(5-formylfurfuryl)ether]、没食子酸乙酯(ethyl gallate)均为首次从龙眼核中分离得到。Objective To isolate individual chemical constituents on Longan seeds and investigate their chemical structures.Methods The compounds from Longan seeds were extracted by different organic solvent systems,and isolated and purified by techniques of column chromatography and recrystallization.Their structures were elucidated by using IR,1H-NMR,13C-NMR and MS,and according to the physical and chemical properties.Results Six chemical constituents were obtained,and four of them were obtained for the first time from the Longan seeds and identified respectively as pentacosane,stigmasterol,bis（5-formylfurfuryl）ether,and ethyl gallate.Conclusion These four compounds were isolated and identified firstly in the Longan seeds.

关 键 词：龙眼核 中药化学成分 

分 类 号：R284[医药卫生—中药学]