前列腺癌和前列腺增生患者血清tPSA及cPSA含量变化及其临床价值  

Concentrations of tPSA and cPSA in patients with prostate cancer and benign prostatic hyperplasia and it's clinical significance

作　　者：蒋长斌[1] 崔邦平[1] 代文莉[1] 刘玉文[1] 杨建华[1] 

机构地区：[1]三峡大学第一临床医学院湖北省宜昌市中心人民医院,湖北宜昌443003

出　　处：《海南医学》2009年第10期8-9,共2页Hainan Medical Journal

摘　　要：目的探讨血清tPSA及cPSA在前列腺癌和前列腺增生患者中的含量变化及其临床价值。方法采用双抗体夹心磁微粒化学发光法分析95例前列腺增生和40例前列腺癌患者的血清tPSA及cPSA的含量,并与55例健康体检者对照。结果前列腺增生组和前列腺癌组与正常对照组间tPSA和cPSA比较差异均具有统计学意义(P<0.01),前列腺增生与前列腺癌组间tPSA和cPSA比较差异均具有统计学意义(P<0.01)。结论cPSA和tPSA对前列腺癌和前列腺增生有重要的鉴别诊断意义。Objective To observe the concentrations of tPSA and ePSA in patients with PCa and BPH. Methods The concentrations of PSA and cPSA were detected according to double - antibody sandwich ehemilumi- neseinee in all of the subjects. And the results were compared among the PCa,BPH and the health volunteers. Re- sults The concentrations of tPSA and cPSA in the Pea, BPH group were signtifieantly different from the health. And the concentrations of tPSA and ePSA in PCa group were signtifieanfly different from the BPH group. Conclu- sion ePSA was effective to discriminate PCa from BPH.

关 键 词：PSA cPSA 前列腺癌 前列腺增生 化学发光法 

分 类 号：R737.25[医药卫生—肿瘤]