一种改进的重叠细胞图像分割研究  

Improved research for overlapping cell images segmentation

作　　者：黄文明[1] 陈庆全[1] 陆荣[2,3] 

机构地区：[1]桂林电子科技大学计算机与控制学院,广西桂林541004 [2]桂林电子科技大学电子工程学院,广西桂林541004 [3]中国科学院微电子研究所,北京100029

出　　处：《计算机工程与应用》2009年第26期163-165,共3页Computer Engineering and Applications

基　　金：国家火炬计划项目No.2006GH041397~~

摘　　要：在医学细胞图像处理中,经常遇到细胞图像重叠现象。传统的分水岭算法存在严重的过分割现象。使用距离变换的分水岭算法能很好地避免过分割现象。考虑到细胞具有类圆形的特点,使用固定的结构元素进行极限腐蚀容易导致细胞失真。使用交替结构元素对重叠细胞进行腐蚀,能准确地标记出单个细胞种子,同时能避免细胞因腐蚀而失真。最后使用膨胀处理找出重叠细胞的分界线。实验结果表明,算法有效地避免了过分割现象,并提高了分割处理的准确度。Cell images processing in medical often appear that the cell images have overlapped each other.The traditional watershed algorithm always results in serious over segmentation phenomenon.It can avoid over segmentation well by using the distance transformation watershed algorithm.Considering that cells have a similar circular characteristic in common,doing the Ultra-erosion by using the fixed structuring element can result in ceils＇ distortion easily.Eroding the overlapping cells by using the ahernant structuring element can mark every single cell seed accurately,and it can avoid the ceils＇ distortion by eroding effectively.Finally,it finds out the overlapping cells＇ watershed by using the dilation.The results show that the algorithm can avoid over segmentation effectively and improve the measurement accuracy.

关 键 词：重叠细胞 分水岭算法 距离变换 极限腐蚀 

分 类 号：TP391[自动化与计算机技术—计算机应用技术]