分枝杆菌降解植物甾醇制备雄烯二酮转化过程研究  

DEGRADATION OF PHYTOSTERIL INTO ANDROSTENEDIONE BY Mycobacterium SP-UV-8

作　　者：杨英[1,2] 姜绍通[2] 魏兆军[2] 赵妍嫣[2] 孙晓明[2] 

机构地区：[1]安徽建筑工业学院环境工程系,安徽合肥230022 [2]合肥工业大学生物与食品工程学院,安徽合肥230009

出　　处：《核农学报》2009年第5期805-808,共4页Journal of Nuclear Agricultural Sciences

基　　金：国家科技支撑计划项目(2007BAD34B01);国家高技术研究发展计划"863"项目(2007AA10Z361);安徽省自然科学基金项目(070413265X);安徽省科技厅2009年度科技攻关项目(08020203004)

摘　　要：在分批发酵中研究了分枝杆菌(Mycobacterium sp-UV-8)的菌体生长、基质消耗及产物生成的特征,基于Logistic方程和Leudeking-piret方程建立了描述分批发酵过程的动力学模型及模型参数,并对试验数据与模型进行验证比较,结果平均相对误差均小于7%,模型计算值与试验数据拟合良好,基本反映了Mycobacterium sp-UV-8分批发酵过程的动力学特征,表现出很好的适用性,为产业化设计和生产提供了可靠的保障。The fermentation process of Mycobacterium sp-UV-8 was studied in batch system, and a kinetic model was proposed based on the Logistic and Leudeking-piret equations for microorganism growth, product formation and substrate consumption. Depending on the evaluated model parameters, the model appears to provide a reasonable description for the fermentation process,and the average relative error was no more than 7%. The calculated results of models were compared satisfactorily with experimental data, which offers assurance for the industrial design and production throught degradation of phytosterol by Mycobacterium sp-UV-8.

关 键 词：生物量 植物甾醇 发酵动力学 数学模型 雄烯二酮 

分 类 号：TQ464[化学工程—制药化工]