增殖性玻璃体视网膜病变发病因素的研究进展  

Current Advances about the Risk Factors of Proliferative Vitreoretinopathy

作　　者：贾媛媛[1,2] 高晓唯[2] 

机构地区：[1]石河子大学医学院,新疆石河子832003 [2]解放军474医院眼科中心,乌鲁木齐830011

出　　处：《医学综述》2009年第20期3077-3080,共4页Medical Recapitulate

摘　　要：增殖性玻璃体视网膜病变(PVR)是孔源性视网膜脱离手术失败的最主要原因,也是眼外伤、糖尿病及血管性、炎症性视网膜病变的一种结局,是眼科常见的致盲性疾病之一。其发生、发展是多种因素共同作用的结果,如视网膜色素上皮细胞、神经胶质细胞和一些炎性细胞因子的参与等。这些细胞和因子在视网膜表面和玻璃体内游走、附着、增殖,形成纤维膜并且收缩,造成牵拉性视网膜脱离。Proliferative vitreoretinopathy（PVR）,which is a result of the ocular trauma,diabetes and vascular or inflammatory retinopathy,is the main reason responsible for the failure of rhegmatogenous retinal detachment surgery.PVR is one of the common eye diseases which can cause blindness.The development of PVR involves a variety of factors,such as the involvement of retinal pigment epithelium（RPE）,glial cells and inflammatory cytokines.The walk,attachment and proliferation of these cells and cytokines in the surface of retina and vitreous body,and subseqent fibrous membrane formation and contraction,result in the tractional detachment of retina.We discuss the current advances about the risk factors in PVR.

关 键 词：增殖性玻璃体视网膜病变 发病因素 

分 类 号：R774.1[医药卫生—眼科]