原发性大肠恶性淋巴瘤临床特点与误诊分析  

Clinicopathological and Misdiagnosis Analysis of Primary Colorectal Malignant Lymphoma

作　　者：马升高[1] 孟凡升[1] 胡祥鹏[1] 吴建胜[1] 吴明[1] 韩清锡[1] 

机构地区：[1]温州医学院附属第一医院消化内科,浙江省温州市325000

出　　处：《中国全科医学》2009年第20期1887-1889,共3页Chinese General Practice

摘　　要：目的探讨原发性大肠恶性淋巴瘤的临床特点,并分析其误诊原因,总结避免误诊的措施。方法对我院2000—2008年收集的21例原发性大肠淋巴瘤患者的病历资料进行回顾性分析。结果原发性大肠恶性淋巴瘤的临床表现以腹部肿块、腹痛、体质量下降以及血便、腹胀为主要特点,17例患者术前均未确诊,术前误诊时间7d～30个月。临床易误诊为癌与炎症性肠病。发病部位:肿瘤位于回盲部13例,升结肠4例,横结肠1例,降结肠1例,直肠1例,全结肠均累及1例。病理类型均为非霍奇金淋巴瘤。结论原发性大肠恶性淋巴瘤的临床特点缺乏特异性,容易误诊,内镜活检和手术标本的病理学检查是目前确诊原发性大肠恶性淋巴瘤的主要依据。Objective To investigate the clinicopathological features of primary colorectal malignant lymphoma and its misdiagnoses.Methods The clinical data of 21 cases collected from Jan.2000 to Dec.2008 were analyzed retrospectively.Results Twenty-one patients（male to female ratio was 2：1） had primary colorectal malignant lymphoma,presenting mainly with abdominal mass,abdominal pain,decreased body weight,blood stools and abdominal distension.Seventeen patients were not diagnosed definitely before operation,misdiagnosing time lasting 7 d ～30 months.Primary colorectal malignant lymphomas were easy to be misdiagnosed as cancers or inflammatory bowel disease.Tumors were located in ileocecal junction in 13 patients,ascending colon in 4,transverse colon in 1,descending colon in 1,rectum in 1,the entire colon involved in 1.Pathological types were all non-Hodgkin＇s lymphoma.Conclusion The clinical features of primary colorectal malignant lymphoma are lack of specificity,and easy to be misdiagnosed.Pathological examination of endoscopic biopsy and surgical specimens are the main bases for definite diagnoses of primary colorectal malignant lymphoma.

关 键 词：大肠肿瘤 淋巴瘤 非霍奇金 误诊 

分 类 号：R735.3[医药卫生—肿瘤]