脑胶质瘤SRS治疗后加速再增殖的初步认识  

The rapid proliferation of the glioma after sterotactic radiosurgery (SRS) treatment

作　　者：周俊领[1] 张宗昆[1] 刘志兴[1] 刘中远[1] 张树春[1] 刘献志 

机构地区：[1]中国人民解放军150医院,河南医科大学第一附属医院神经外科

出　　处：《功能性和立体定向神经外科杂志》1998年第4期18-20,共3页

摘　　要：目的：探讨脑胶质细胞瘤立体定向放射外科（ＳＲＳ）治疗后加速再增殖的问题。方法：研究１９９４年４月～１９９７年２月间２１例ＳＲＳ治疗后复发再手术治疗的病例，本组均行ＭＲＩ检查、手术切除、病理检查。在ＭＲＩ片上测量肿瘤的大小。结果：ＳＲＳ治疗后脑胶质瘤复发迅速，周边脑组织大片水肿，瘤细胞增殖活跃，侵润性增强。结论：（１）中枢神经系统恶性肿瘤的放射治疗也存在加速再增殖的问题；（２）ＳＲＳ治疗脑胶质瘤应严格掌握适应证。Objective Purpose: To Study the rapid proliferation of the gliomaafter SRS treatment Materials and methods: Reviewing the cases of 21 patients who have received operation after they have relapses, all these patients had been given MRI examination before the operation to remove the glioma and pathology postoperatively Results: The glioma recurred rapidly after SRS with serions peripheral cerebral edoma, rapid proliferation of tumor cells, stronger invesiveness Conclusion: (1) Rapid proliferetion also appears after SRS treatment of central nervous system tumors (2) We should know the indication well in the SRS treatment of the gliomas

关 键 词：脑胶质瘤 立体定向 放射外科 加速再增殖 

分 类 号：R739.410.5[医药卫生—肿瘤]