豚鼠颞叶出血前后听觉中潜伏期反应变化  

Study on auditory middle latency response before and after temporal hemorrhage in guinea pigs

作　　者：胡艾君[1] 包仕尧[1] 赵合庆[1] 支海红[1] 张志琳[1] 

机构地区：[1]苏州医学院附属第二医院,江苏苏州215004

出　　处：《临床脑电学杂志》1998年第4期227-229,共3页

摘　　要：目的：观察豚鼠颞叶出血前后听觉中潜伏期反应（MLR）变化。方法：通过豚鼠未肝素化自体血回注建立颞叶出血模型，监测其出血前后听觉MLR的主要波形A波的变化。结果：①A波起源于颞部听皮层，正常豚鼠潜伏期大约在12～15ms之间；②颞叶出血后A波潜伏期（17～23ms）明显延长，甚至A波消失。结论：MLR的A波是反映颞叶出血的早期、客观、无创伤的一项重要指标。Objectives:To study the changes of auditory middle latency response(MLR) before and after temporal hemorrhage in guinea pigs.Methods:The temporal hemprrhage model in guinea pigs was constructed by autohenic injection of nonheparinized arterial blood.The changes of wave A (the main wave form,which was Originated from the auditory cortex of the temporal lobe) on MLR were monitoho.Results:The latency of wave A was about 12-15 ms in normal guinea pigr.The latency was significantly prologyed, even wave A was disappeared, and temporal hemorrhage.Conclusions:wave A on MLR might be an objective, non-invasive and early impotent index in reflecting temporal damage.

关 键 词：脑出血 豚鼠 颞叶出血 BAEP 

分 类 号：R743.34[医药卫生—神经病学与精神病学]