中药材小驳骨的质量标准研究  

The Studies on the Quality Standards of Gendarussa Vulgaris Ness

作　　者：江秀娟[1] 林惠蓉[2] 陈新[1] 

机构地区：[1]广州市药品检验所二分所,广东广州510250 [2]广东省药品检验所,广东广州510180

出　　处：《临床医学工程》2009年第10期26-28,共3页Clinical Medicine & Engineering

摘　　要：目的研究中药材小驳骨的质量标准,为新版《中国药典》提供可参考的数据资料。方法按《中国药典》2005年版附录IX H水分测定第一法、附录IX K灰分测定法、附录XA浸出物测定法对中药材小驳骨的水分、总灰分、酸不溶性灰分、水溶性浸出物进行测定,并按附录VIB对薄层鉴别进行方法研究。结果10批小驳骨测试样品中水分含量为9.0%～12.0%,平均值10.6%;总灰分为4.7%～16.7%,平均值9.3%;酸不溶性灰分结果为0.22%～1.3%,平均值0.53%;热浸法水溶性浸出物量为10.6%～28.0%,平均值为17.9%。结论明确其基源为爵床科植物小驳骨Gendarussa vulgaris Ness,并对药材正名、性状、鉴别、检查、浸出物等质量标准项目进行了全面的对比研究和归纳,中药材小驳骨的水分不得过13.0%,总灰分不得过l1.0%,酸不溶性灰分不得过2.0%,热浸法水溶性浸出物不得过8.0%。Objective To establish and perfect the quality standard system of Gendarussa vulgaris Ness and to provide the reference datas to the new Chinese Pharmacopeoia. Method Edematous amaenorrhea, total ashes, acid endurable ashes, water-soluble extracts of the Gendarus- sa vulgaris Ness samples were investigated with the first edematous amanorrhea detemfination method in Appendix IXI-I ashes determination method in Appendix IXK and extract detemfination method in Appendix XA in Chinese Pharmacopeoia published in 2005. Results The edema- tous amaenorrhea were 9.0%~ 12%, with an anavenage value of 10.06% ; the total ashes were 4.7%~ 16.7%, with an average volue of 9.3%; the acid-endurable ashes were 0.22%~ 1.3%, with an average value of 0.53%; the water-soluble extracts in hot water were10.6%~ 28%, with an average value of 17.9%. Conclusions It is suggested that edematous amaenorrhea should not be higher than 13.0%, total ashes should not be higher than 11.0%, acid-endurable ashes should not be higher than 2%, water-soluble exfracts in hot water should not be lower than 8% conceming the establishment and perfection of Gendarussa vulgaris Ness quality standard system.

关 键 词：小驳骨 中药材 质量标准 

分 类 号：R737.9[医药卫生—肿瘤]