广州市肥胖及超重儿童青少年代谢综合征患病情况调查  

Prevalence of metabolic syndrome among overweight and obese children and adolescents in Guangzhou

作　　者：刘烈华[1] 李延兵[1] 严晋华[2] 翁建平[2] 

机构地区：[1]中山大学附属第一医院内分泌代谢科,广州510080 [2]中山大学附属第三医院内分泌代谢科

出　　处：《中华全科医师杂志》2009年第10期698-701,共4页Chinese Journal of General Practitioners

基　　金：广州市科技计划项目资助（200521-E0041）

摘　　要：目的了解广州超重和肥胖儿童、青少年代谢综合征（MS）和代谢异常的患病情况。方法对439名6～18岁儿童、青少年（肥胖者129名，超重者115名，正常对照者195名）行身高、体重、腰围、臀围、血压测量，检测空腹血糖、血脂，并行121服葡萄糖耐量试验。结果①肥胖、超重者MS患病率分别为20．9％（27／129）、10．4％（12／115）；胰岛素抵抗者、非胰岛素抵抗者MS患病率分别为17．9％（35／195）、1．6％（4／244）。MS、各代谢异常患病率和多个代谢异常的聚集均随着体重指数（BMI）的增加及胰岛素抵抗的发生呈增加趋势。②BMI与各代谢指标的相关性更强，可独立预测MS风险。结论广州市肥胖及超重儿童、青少年MS患病率较高；BMI可作为儿童、青少年MS肥胖的评估指标。Objective To know prevalence of metabolic syndrome （MS） and metabolic abnormalities （MA） in overweight and obese children and adolescents in Guangzhou, China. Methods Totally, 439 children and adolescents aged six to 18 years were enrolled, including 129 obese, 115 overweight and 195 normal control ones. Their body height, body weight, waist circumference, hip circumference and blood pressure were measured, as well as their fasting blood glucose （ FBG ） , lipid profiles and oral glucose tolerance test （OGTT）. Results ①Prevalence of MS in overweight and obese children and adolescents was 20. 9 % （27/129） and 10. 4 % （12/115）, respectively, 17.9 % （35/195） and 1.6 % （4/244） in those with insulin resistance and non-insulin resistance, respectively. Prevalence of MS, each component of MA and cluster of each components of MA all increased in linear trend with their body mass index （BMI） or insulin resistance increasing. ② BMI correlated with all metabolic indicators and could independently predict risk of MS. Conclusions Prevalence of MS among overweight and obese children and adolescents in Guangzhou was considerably high, and BMI can be used as a suitable index for their obesity assessment in MS diagnosis.

关 键 词：代谢综合征X 儿童 青少年 超重 

分 类 号：R589[医药卫生—内分泌]