三七花蕾化学成分的分离与鉴定  

Isolation and identification of chemical constituents from flower buds of Panax notoginseng

作　　者：张冰[1] 陈晓辉[1] 毕开顺[1] 

机构地区：[1]沈阳药科大学药学院,辽宁沈阳110016

出　　处：《沈阳药科大学学报》2009年第10期775-777,共3页Journal of Shenyang Pharmaceutical University

摘　　要：目的对三七(Panax notoginseng(Burk.)F.H.Chen)花蕾的化学成分进行研究。方法利用体积分数为75%提取、D101大孔吸附树脂柱、硅胶柱、Sephadex LH-20柱色谱等方法分离纯化,根据理化性质和光谱数据确定化合物的结构。结果分离得到6个化合物,分别鉴定为:山奈酚-3-O-β-D-半乳糖(2→1)葡萄糖苷(kaempferol 3-O-(2″-β-D-galactopyranosyl)-β-D-glucopyranoside,1)、槲皮素-3-O-β-D-半乳糖(2→1)葡萄糖苷(quercetin3-O-(2″-β-D-galactopyranosy l)-β-D-g lucopyranoside,2)、鸟嘌呤核苷(guanosine,3)、腺嘌呤核苷(adenosine,4)、β-谷甾醇(-βsitostero l,5)、胡萝卜苷(daucostero l,6)。结论化合物1、2为首次从该植物花蕾中分离得到,化合物3、4为首次从该植物中分离得到。Objective To study the chemical constituents from the flower buds of Panax notoginseng. Methods The material was decocted with water, then isolated and purified by various chromatographic methods. All compounds were identified on the basis of spectral analysis and physicochemical data. Results Six compounds were elucidated as kaempferol 3-O-（ 2＂-β-D-galactopyranosyl ） -β-D-glucopyranoside （ 1 ）, quercetin 3-0- （2＂-fl-D-galactopyranosyl） -β-D-glucopyranoside （2）, guanosine （ 3 ）, adenosine （ 4 ） ,β-sitosterol （ 5 ） and daucosterol （6）. Conclusions Compounds 1 and 2 are obtained from the flower buds of this plant for the first time and compounds 3 and 4 are isolated from this plant for the first time.

关 键 词：三七 花蕾 化学成分 结构鉴定 

分 类 号：R914[医药卫生—药物化学] R284[医药卫生—药学]